Thermo Scientific Chemicals Chloramphenicol, 98%

Product Code	Brand	Quantity	Packaging
10368030	Thermo Scientific Chemicals 227920250	25 g	Glass Bottle
10277523	Thermo Scientific Chemicals 227921000	100 g	Glass Bottle
11906911	Thermo Scientific Chemicals 227925000	500 g	Glass Bottle

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Chloramphenicol is an organochloride compound that contains a nitrobenzene ring
• Chloramphenicol acts as a bacteriostatic by binding the 50S ribosomal subunit and preventing peptide formation
• Stops peptidyltransferase activity by complexing to 50S subunit

Applications

• Intended for molecular and microbiology applications such as antibiotic resistance gene testing and selective growth experiments and as a selection agent in bacterial cell culture
• For research use only

Chemical Identifiers

• CAS: 56-75-7
• Molecular Weight (g/mol): 323.126
• InChI Key: WIIZWVCIJKGZOK-RKDXNWHRSA-N
• PubChem CID: 5959
• IUPAC Name: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

• Molecular Formula: C11H12Cl2N2O5
• MDL Number: MFCD00078159
• Synonym: Chloromycetin, D(-)-threo-2, 2-Dichloro-N-[β-hydroxy-α-(hydroxy-methyl)-p-nitrophenylethyl]acetamide
• ChEBI: CHEBI:17698
• SMILES: C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

Specifications

• Type: Chloramphenicol
• Melting Point: 149.0°C to 153.0°C
• Assay Percent Range: 98%
• MDL Number: MFCD00078159
• Solubility Information: Solubility in water: 2.5g/L (25°C). Other solubilities: 150.8 mg/mL propylene glycol, soluble in methanol, ethanol, butanol, acetone and, ethyl acetate - slightly soluble in ether, insoluble in benzene and petroleum ether
• SMILES: C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
• Molecular Weight (g/mol): 323.126
• ChEBI: CHEBI:17698
• Percent Purity: 98%

• CAS: 56-75-7
• Specific Rotation: + 18.50
• Molecular Formula: C11H12Cl2N2O5
• Synonym: Chloromycetin, D(-)-threo-2, 2-Dichloro-N-[β-hydroxy-α-(hydroxy-methyl)-p-nitrophenylethyl]acetamide
• InChI Key: WIIZWVCIJKGZOK-RKDXNWHRSA-N
• IUPAC Name: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• PubChem CID: 5959
• Formula Weight: 323.13
• Chemical Name or Material: Chloramphenicol

Safety and Handling

GHS H Statement:
May cause cancer.

GHS P Statement:
Obtain special instructions before use.
IF exposed or concerned: Get medical advice/attention.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

Product Identifier

• Chloramphenicol

Signal Word

• Danger

Hazard Category

• Carcinogenicity Category 1B

Hazard Statement

• H350-May cause cancer.

Precautionary Statement

• P201-Obtain special instructions before use.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only