Thermo Scientific Chemicals Chloramphenicol, 98%

Description

Chloramphenicol, CAS # 56-75-7, is a preparation of the broad-spectrum, semisynthetic antibiotic.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Chloramphenicol is an organochloride compound that contains a nitrobenzene ring
• Chloramphenicol acts as a bacteriostatic by binding the 50S ribosomal subunit and preventing peptide formation
• Stops peptidyltransferase activity by complexing to 50S subunit

Applications

• Intended for molecular and microbiology applications such as antibiotic resistance gene testing and selective growth experiments and as a selection agent in bacterial cell culture
• For research use only

Specifications

Chemical Identifiers

• CAS: 56-75-7
• Molecular Formula: C11H12Cl2N2O5
• Molecular Weight (g/mol): 323.126
• MDL Number: MFCD00078159
• InChI Key: WIIZWVCIJKGZOK-RKDXNWHRSA-N
• Synonym: Chloromycetin, D(-)-threo-2, 2-Dichloro-N-[β-hydroxy-α-(hydroxy-methyl)-p-nitrophenylethyl]acetamide
• PubChem CID: 5959
• ChEBI: CHEBI:17698
• IUPAC Name: 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• SMILES: C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

• Type: Chloramphenicol
• Melting Point: 149.0°C to 153.0°C
• Packaging: Glass Bottle
• Specific Rotation: + 18.50 (20.50°C c=6,C2H5OH)
• Quantity: 100 g
• Assay Percent Range: 98%
• Solubility Information: Solubility in water: 2.5g/L (25°C). Other solubilities: 150.8 mg/mL propylene glycol, soluble in methanol, ethanol, butanol, acetone and, ethyl acetate - slightly soluble in ether, insoluble in benzene and petroleum ether
• Formula Weight: 323.13
• Percent Purity: 98%
• Chemical Name or Material: Chloramphenicol

Safety and Handling

Product Identifier

• Chloramphenicol

Signal Word

• Danger

Hazard Category

• Carcinogenicity Category 1B

Hazard Statement

• H350-May cause cancer.

Precautionary Statement

• P201-Obtain special instructions before use.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only