1-Bromo-3-chloropropane, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11484190	Thermo Scientific Alfa Aesar A11395.22	100 g
11440223	Thermo Scientific Alfa Aesar A11395.30	250 g
11494190	Thermo Scientific Alfa Aesar A11395.36	500 g
11430223	Thermo Scientific Alfa Aesar A11395.0B	1000 g
11450223	Thermo Scientific Alfa Aesar A11395.0I	5000 g

Description

1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.

Solubility
Miscible with alcohols, chlorofom and ether. Immiscible with water.

Notes
Incompatible with strong oxidizing, reducing agents, amines, nitrides, azo/diazo compounds, alkali metals and epoxides.

Chemical Identifiers

• CAS: 109-70-6
• Molecular Weight (g/mol): 157.435
• InChI Key: MFESCIUQSIBMSM-UHFFFAOYSA-N
• PubChem CID: 8006
• SMILES: C(CCl)CBr

• Molecular Formula: C3H6BrCl
• MDL Number: MFCD00000998
• Synonym: trimethylene chlorobromide, 1-chloro-3-bromopropane, 3-bromopropyl chloride, 3-chloropropyl bromide, propane, 1-bromo-3-chloro, 3-chloro-1-bromopropane, 3-bromo-1-chloropropane, trimethylene bromide chloride, 1,3-chbp, 1,3-chlorbromopropane
• IUPAC Name: 1-bromo-3-chloropropane

Specifications

• CAS: 109-70-6
• Density: 1.598
• Flash Point: >140°C (284°F)
• Refractive Index: 1.4855
• UN Number: UN2688
• Synonym: trimethylene chlorobromide, 1-chloro-3-bromopropane, 3-bromopropyl chloride, 3-chloropropyl bromide, propane, 1-bromo-3-chloro, 3-chloro-1-bromopropane, 3-bromo-1-chloropropane, trimethylene bromide chloride, 1,3-chbp, 1,3-chlorbromopropane
• InChI Key: MFESCIUQSIBMSM-UHFFFAOYSA-N
• IUPAC Name: 1-bromo-3-chloropropane
• PubChem CID: 8006
• Percent Purity: 99%

• Melting Point: -59°C
• Boiling Point: 142°C to 145°C
• Molecular Formula: C3H6BrCl
• MDL Number: MFCD00000998
• Beilstein: 605278
• Solubility Information: Miscible with alcohols,chlorofom and ether. Immiscible with water.
• SMILES: C(CCl)CBr
• Molecular Weight (g/mol): 157.435
• Formula Weight: 157.44
• Chemical Name or Material: 1-Bromo-3-chloropropane

Safety and Handling

GHS H Statement
H331-H302
Toxic if inhaled.
Harmful if swallowed.

P201-P202-P210-P235-P261-P264b-P270-P271-P281-P301+P312-P304+P340-P308+P313-P311-P330-P370+P378q-P501c

H227-H302-H331-H335-H341

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: 1-BROMO-3-CHLOROPROPANE

missing translation for 'einecsNumber' : 203-697-1

missing translation for 'rtecsNumber' : TX4113000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• 1-Bromo-3-chloropropane

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• LONG-TERM AQUATIC HAZARD Chronic 3
• Germ cell mutagenicity Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H331-Toxic if inhaled.
• H335-May cause respiratory irritation.
• H341-Suspected of causing genetic defects.
• H412-Harmful to aquatic life with long lasting effects.

Precautionary Statement

• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P311-Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contains : 1-Bromo-3-chloropropane

RUO – Research Use Only