1-Bromo-3-chloropropane, 99%, Thermo Scientific Chemicals

Description

1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Bromo-3-chloropropane is used in the preparation active pharmaceutical ingredient intermediate such as gemfibrozil and reproterol. It is also involved in the preparation of cardiovascular diseases and analgesic drugs materials. It is utilized as a phase separation reagent for the isolation of ribonucleic acid (RNA) in high quality. It is considered as a replacement of chloroform in nucleic acid separations.

Solubility
Miscible with alcohols, chlorofom and ether. Immiscible with water.

Notes
Incompatible with strong oxidizing, reducing agents, amines, nitrides, azo/diazo compounds, alkali metals and epoxides.

Specifications

Chemical Identifiers

• CAS: 109-70-6
• Molecular Formula: C3H6BrCl
• Molecular Weight (g/mol): 157.435
• MDL Number: MFCD00000998
• InChI Key: MFESCIUQSIBMSM-UHFFFAOYSA-N
• Synonym: trimethylene chlorobromide, 1-chloro-3-bromopropane, 3-bromopropyl chloride, 3-chloropropyl bromide, propane, 1-bromo-3-chloro, 3-chloro-1-bromopropane, 3-bromo-1-chloropropane, trimethylene bromide chloride, 1,3-chbp, 1,3-chlorbromopropane
• PubChem CID: 8006
• IUPAC Name: 1-bromo-3-chloropropane
• SMILES: C(CCl)CBr

• Melting Point: -59°C
• Density: 1.598
• Boiling Point: 142°C to 145°C
• Flash Point: >140°C (284°F)
• Refractive Index: 1.4855
• Quantity: 250 g
• UN Number: UN2688
• Beilstein: 605278
• Solubility Information: Miscible with alcohols,chlorofom and ether. Immiscible with water.
• Formula Weight: 157.44
• Percent Purity: 99%
• Chemical Name or Material: 1-Bromo-3-chloropropane

Safety and Handling

Product Identifier

• 1-Bromo-3-chloropropane

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• LONG-TERM AQUATIC HAZARD Chronic 3
• Germ cell mutagenicity Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H331-Toxic if inhaled.
• H335-May cause respiratory irritation.
• H341-Suspected of causing genetic defects.
• H412-Harmful to aquatic life with long lasting effects.

Precautionary Statement

• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P311-Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contains : 1-Bromo-3-chloropropane

RUO – Research Use Only