Estrogen Receptor Ab-11 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor Ab-11, Mouse Monoclonal Antibody.

Product Code	Brand	Form	Quantity
12651137	Epredia MS-354-P1ABX	Concentrated	100 μL
12641137	Epredia MS-354-P1	Concentrated	500 μL
12631137	Epredia MS-354-P	Concentrated	1 mL
12621137	Epredia MS-354-P0	Concentrated	100 μL
12671137	Epredia MS-354-PABX	Concentrated	200 μL
12601147	Epredia MS-354-R7	Prediluted	7 mL

Description

The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Mouse

Clone: 1D5

Isotype: IgG1/κ

Species Reactivity: Human, Monkey, Mouse and Rat. Others not known.

Epitope: N-terminal domain

Immunogen: Recombinant human estrogen receptor protein

Molecular Weight: 67 kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Specifications

• Antigen: Estrogen Receptor Ab-11
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Regulatory Status: ASR, IVD
• Target Species: Human, Mouse, Non-human Primate, Rat
• Isotype: IgG2a κ

• Clone: 1D5
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Steroids Hormones and Growth Factors
• Immunogen: Recombinant human estrogen receptor protein
• Primary or Secondary: Primary