ZFYVE21 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16883305	Proteintech 24806-1-AP-20UL	20 μL
16873305	Proteintech 24806-1-AP-150UL	150 μL

Description

ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.

Specifications

• Antigen: ZFYVE21
• Applications: Western Blot, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q9BQ24
• Gene ID (Entrez): 79038
• Immunogen: ZFYVE21 Fusion Protein Ag20024
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ZFYVE21

• Concentration: 0.4 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: ZFYVE21
• Gene Symbols: ZFYVE21
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody