Thermo Scientific Chemicals Tripeptidyl Peptidase Inhibitor

Description

Tripeptidyl peptidase Inhibitor is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions, and reversibly inhibits Cln (TPPI). AAF-CMK shows only marginal inhibition of the chymotrypsin-like activity of the proteasome.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• A serine protease inhibitor that acts as a potent, selective, dose-dependent, irreversible inhibitor of tripeptidylpeptidase II

Specifications

Chemical Identifiers

• CAS: 184901-82-4
• Molecular Formula: C₁₆H₂₂ClN₃O₃, C18H23ClF3N3O5
• Synonym: H-AAF-CMK; TPPII Inhibitor

• Quantity: 10 mg
• Description: Off-white
• Content And Storage: -30°C to -10°C
• For Use With (Application): A serine protease inhibitor that acts as a potent, selective, dose-dependent, irreversible inhibitor of tripeptidylpeptidase II
• Formula Weight: 453.90g/mol
• Sensitivity: Light Sensitive
• Product Type: Signal Transduction Reagent
• Form: Solid
• InChI Key: ZFZXFWAYCYJFIZ-UHFFFAOYNA-N
• SMILES: OC(=O)C(F)(F)F.CC(N)C(=O)NC(C)C(=O)NC(CC1=CC=CC=C1)C(=O)CCl
• IUPAC Name: 2-amino-N-{1-[(4-chloro-3-oxo-1-phenylbutan-2-yl)carbamoyl]ethyl}propanamide; trifluoroacetic acid
• Molecular Weight (g/mol): 453.84

Safety and Handling

SDS

RUO – Research Use Only