Triisopropylsilane, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11302157	Thermo Scientific Alfa Aesar L09585.06	5 g
11312157	Thermo Scientific Alfa Aesar L09585.14	25 g
11322157	Thermo Scientific Alfa Aesar L09585.22	100 g

Description

Triisopropylsilane is used as a protecting group in peptide synthesis and is also used as a reducing agent for the selective reduction of anomeric C-phenyl ketals. It is used in the selective silylation of primary hydroxyl groups without affecting the secondary hydroxyl group. It is used in the preparation of anti-1,2-diols catalyzed by a Ni(O) N-heterocyclic carbine complex with high diastereoselectivity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Triisopropylsilane is used as a protecting group in peptide synthesis and is also used as a reducing agent for the selective reduction of anomeric C-phenyl ketals. It is used in the selective silylation of primary hydroxyl groups without affecting the secondary hydroxyl group. It is used in the preparation of anti-1,2-diols catalyzed by a Ni(O) N-heterocyclic carbine complex with high diastereoselectivity.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids and strong oxidizing agents.

Chemical Identifiers

• CAS: 6485-79-6
• Molecular Weight (g/mol): 158.36
• InChI Key: YDJXDYKQMRNUSA-UHFFFAOYSA-N
• PubChem CID: 6327611

• Molecular Formula: C9H22Si
• MDL Number: MFCD00009657
• Synonym: triisopropylsilane, tris propan-2-yl silane, triisopropyl silane, tri propan-2-yl silicon, tri-isopropylsilyl radical, triisopropylsilyl, tri-iso-propylsilane, ambotzrl-1102, pubchem12855
• SMILES: CC(C)[SiH](C(C)C)C(C)C

Specifications

• Boiling Point: 166°C
• Molecular Formula: C9H22Si
• MDL Number: MFCD00009657
• Beilstein: 1733718
• Synonym: triisopropylsilane, tris propan-2-yl silane, triisopropyl silane, tri propan-2-yl silicon, tri-isopropylsilyl radical, triisopropylsilyl, tri-iso-propylsilane, ambotzrl-1102, pubchem12855
• InChI Key: YDJXDYKQMRNUSA-UHFFFAOYSA-N
• IUPAC Name: tris(propan-2-yl)silane
• PubChem CID: 6327611
• Percent Purity: 98%
• Refractive Index: 1.434
• Chemical Name or Material: Triisopropylsilane

• CAS: 6485-79-6
• Linear Formula: [(CH₃)₂CH]₃SiH
• UN Number: UN1993
• Flash Point: 35°C (95°F)
• Solubility Information: Immiscible with water.
• SMILES: CC(C)[SiH](C(C)C)C(C)C
• Molecular Weight (g/mol): 158.36
• Formula Weight: 158.36
• Odor: Mild
• Density: 0.773

Safety and Handling

GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapor.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c

H226-H315-H319-H335

missing translation for 'dotInformation' : Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

RUO – Research Use Only