THOC1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16807633	Proteintech 10920-1-AP-20UL	20 μL
16897623	Proteintech 10920-1-AP-150UL	150 μL

Description

This antibody recognizes the 84 kDa THOC1 protein.

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.

Specifications

• Antigen: THOC1
• Applications: Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: P59924, Q8R3N6, Q96FV9
• Gene ID (Entrez): 225160, 291797, 9984
• Immunogen: THOC1 Fusion Protein Ag1352
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: THOC1

• Concentration: 0.33 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: HPR1, hTREX84, Nuclear matrix protein p84, P84, P84N5, THO complex 1, THO complex subunit 1, Tho1, THOC1
• Gene Symbols: Thoc1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody