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Tapasin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA552382
Additional Details : Weight : 0.02000kg
Descripción
Immunogen sequence: QEGTYLATIH LPYLQGQVTL ELAVYKPPKV SLMPATLARA APGEAPPELL CLVSHFYPSG GLEVEWELRG GPGGRSQKAE GQRWLSALRH HSDGSVSLSG HLQPPPVTTE QHGARYACRI HHPS Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 77%.
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.Especificaciones
Tapasin | |
Polyclonal | |
Unconjugated | |
TAPBP | |
D17Wsu91e; DADB-159G18.7; NGS17; NGS-17; similar to Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein) (NGS-17); TAP binding protein; TAP binding protein (tapasin); TAPA; tapasin; TAP-associated protein; TAP-binding protein; Tapbp; TPN; TPSN | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
6892 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O15533 | |
TAPBP | |
Recombinant protein corresponding to Human Tapasin | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only