Spermine, 97%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11385325	Thermo Scientific Alfa Aesar L19562.03	1 g
11395325	Thermo Scientific Alfa Aesar L19562.06	5 g

Description

Binds to the polyamine modulatory site of NMDA Spermine is essential for both normal and neoplastic tissue growth. It is involved in the modulation of calcium-dependent immune processes. It plays an important role in cellular proliferation and differentiation as well as inhibits neuronal nitric oxide synthase (nNOS).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Binds to the polyamine modulatory site of NMDA Spermine is essential for both normal and neoplastic tissue growth. It is involved in the modulation of calcium-dependent immune processes. It plays an important role in cellular proliferation and differentiation as well as inhibits neuronal nitric oxide synthase (nNOS).

Solubility
Soluble in chloroform, methanol, water and lower alcohols. Insoluble in ether, benzene and petroleum ether.

Notes
Air sensitive and hygroscopic. Store in a cool place. Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

Chemical Identifiers

• CAS: 71-44-3
• Molecular Weight (g/mol): 202.35
• InChI Key: PFNFFQXMRSDOHW-UHFFFAOYSA-N
• PubChem CID: 1103
• IUPAC Name: N,N'-bis(3-aminopropyl)butane-1,4-diamine

• Molecular Formula: C10H26N4
• MDL Number: MFCD00008215
• Synonym: spermine, gerontine, musculamine, neuridine, spermin, 4,9-diaza-1,12-dodecanediamine, diaminopropyltetramethylenediamine, n,n'-bis 3-aminopropyl-1,4-butanediamine, spermine, puriss, 1,4-butanediamine, n,n'-bis 3-aminopropyl
• ChEBI: CHEBI:15746
• SMILES: NCCCNCCCCNCCCN

Specifications

• CAS: 71-44-3
• Boiling Point: 150°C (5 mmHg)
• Molecular Formula: C10H26N4
• UN Number: UN3259
• Sensitivity: Air sensitive; Hygroscopic
• Synonym: spermine, gerontine, musculamine, neuridine, spermin, 4,9-diaza-1,12-dodecanediamine, diaminopropyltetramethylenediamine, n,n'-bis 3-aminopropyl-1,4-butanediamine, spermine, puriss, 1,4-butanediamine, n,n'-bis 3-aminopropyl
• InChI Key: PFNFFQXMRSDOHW-UHFFFAOYSA-N
• IUPAC Name: N,N'-bis(3-aminopropyl)butane-1,4-diamine
• PubChem CID: 1103
• Formula Weight: 202.35
• Chemical Name or Material: Spermine

• Melting Point: 28°C to 30°C
• Flash Point: >110°C (230°F)
• MDL Number: MFCD00008215
• Beilstein: 1751791
• Merck Index: 14,8743
• Solubility Information: Soluble in chloroform,methanol,water and lower alcohols. Insoluble in ether,benzene and petroleum ether.
• SMILES: NCCCNCCCCNCCCN
• Molecular Weight (g/mol): 202.35
• ChEBI: CHEBI:15746
• Percent Purity: 97%

Safety and Handling

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

H314-H335

missing translation for 'dotInformation' : Hazard Class: 8; Packaging Group: II

missing translation for 'einecsNumber' : 200-754-2

missing translation for 'rtecsNumber' : EJ7175000

missing translation for 'tsca' : Yes

Recommended Storage : Keep cold

Product Identifier

• Spermine

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Spermine

RUO – Research Use Only