Spermidine, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11439396	Thermo Scientific Alfa Aesar A19096.03	1 g
11449396	Thermo Scientific Alfa Aesar A19096.06	5 g
11459396	Thermo Scientific Alfa Aesar A19096.14	25 g
15423187	Thermo Scientific Alfa Aesar A19096.22	100 g

Description

Binds to the polyamine modulatory site of NMDA Spermidine is used in electroporation during transferring the DNA into the cell under the electrical impulse. It is also used for purification of DNA-binding proteins. It combines with calcium chloride and utilized for the precipitation of DNA onto microprojectiles for bombardment with a gene gun. It plays an important role to reduce the amount of aging in yeast, flies, worms, and human immune cells by inducing autophagy. It serves as a precursor of spermine and essential for both normal and neoplastic tissue growth.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Binds to the polyamine modulatory site of NMDA Spermidine is used in electroporation during transferring the DNA into the cell under the electrical impulse. It is also used for purification of DNA-binding proteins. It combines with calcium chloride and utilized for the precipitation of DNA onto microprojectiles for bombardment with a gene gun. It plays an important role to reduce the amount of aging in yeast, flies, worms, and human immune cells by inducing autophagy. It serves as a precursor of spermine and essential for both normal and neoplastic tissue growth.

Solubility
Miscible with water, ethanol and ether.

Notes
Hygroscopic. Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

Chemical Identifiers

• CAS: 124-20-9
• Molecular Weight (g/mol): 145.25
• InChI Key: ATHGHQPFGPMSJY-UHFFFAOYSA-N
• PubChem CID: 1102
• IUPAC Name: N'-(3-aminopropyl)butane-1,4-diamine

• Molecular Formula: C7H19N3
• MDL Number: MFCD00008229
• Synonym: spermidine, 1,5,10-triazadecane, 4-azaoctamethylenediamine, spermidin, 4-azaoctane-1,8-diamine, n1-3-aminopropyl butane-1,4-diamine, 1,4-butanediamine, n-3-aminopropyl, n-3-aminopropyl butane-1,4-diamine, n-3-aminopropyl-1,4-butane-diamine, 1,4-diaminobutane, n-3-aminopropyl
• ChEBI: CHEBI:16610
• SMILES: NCCCCNCCCN

Specifications

• CAS: 124-20-9
• Density: 0.925
• Flash Point: >110°C (230°F)
• Refractive Index: 1.479
• UN Number: UN2735
• Sensitivity: Air sensitive
• Synonym: spermidine, 1,5,10-triazadecane, 4-azaoctamethylenediamine, spermidin, 4-azaoctane-1,8-diamine, n1-3-aminopropyl butane-1,4-diamine, 1,4-butanediamine, n-3-aminopropyl, n-3-aminopropyl butane-1,4-diamine, n-3-aminopropyl-1,4-butane-diamine, 1,4-diaminobutane, n-3-aminopropyl
• InChI Key: ATHGHQPFGPMSJY-UHFFFAOYSA-N
• IUPAC Name: N'-(3-aminopropyl)butane-1,4-diamine
• PubChem CID: 1102
• Formula Weight: 145.25
• Chemical Name or Material: Spermidine

• Melting Point: 22°C to 25°C
• Boiling Point: 128°C to 130°C (14 mmHg)
• Molecular Formula: C7H19N3
• MDL Number: MFCD00008229
• Beilstein: 1698591
• Merck Index: 14,8742
• Solubility Information: Miscible with water,ethanol and ether.
• SMILES: NCCCCNCCCN
• Molecular Weight (g/mol): 145.25
• ChEBI: CHEBI:16610
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

H314-H335

missing translation for 'dotInformation' : Hazard Class: 8; Packaging Group: II

missing translation for 'einecsNumber' : 204-689-0

missing translation for 'rtecsNumber' : EJ7000000

missing translation for 'tsca' : Yes

Recommended Storage : Keep cold; Store under Nitrogen

Product Identifier

• Spermidine

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : N-(3-aminopropyl)-1,4-Butanediamine

RUO – Research Use Only