Thermo Scientific Chemicals Rifampin, 95%

Description

Rifampin (rifampicin), CAS # 13292-46-1, is a synthetic rifamycin antibiotic that works by inhibiting RNA and DNA synthesis and exhibits activity against the tuberculosis microbe.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Rifampin is a rifamycin class antibiotic synthesized to resemble the compound isolated from Amycolatopsis rifamycinica

Applications

• Rifampin can be used as a bacteriostatic that prevents RNA and DNA synthesis, particularly in mycobacteria

• It may also act as an antineoplastic, a neuroprotective, and inhibitor of angiogenesis

Specifications

Chemical Identifiers

• CAS: 13292-46-1
• Molecular Formula: C43H58N4O12
• Molecular Weight (g/mol): 822.953
• InChI Key: FZYOVNIOYYPUPY-HRJPTAQKSA-N
• PubChem CID: 131839595
• SMILES: CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C

• Type: Rifampicin
• Melting Point: 183.0°C
• Infrared Spectrum: Authentic
• Loss on Drying: 2% max. (100 mg, 60°C, 4 h) (vacuum)
• Quantity: 5 g
• Solubility Information: Solubility in water: slightly soluble.
• Formula Weight: 822.94
• Percent Purity: 95%
• Chemical Name or Material: Rifampin

Safety and Handling

Product Identifier

• Rifampin

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H302-Harmful if swallowed.

Precautionary Statement

• P270-Do not eat, drink or smoke when using this product.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

RUO – Research Use Only