Pyrophosphoryl chloride, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11358027	Thermo Scientific Alfa Aesar 022362.02	0.5 g
11348027	Thermo Scientific Alfa Aesar 022362.06	5 g
11368027	Thermo Scientific Alfa Aesar 022362.14	25 g

Description

Pyrophosphoryl chloride serves as a reductive chlorination reagent used in the synthesis of quetiapine. It acts as a phosphorylating agent involved in nucleoside synthesis. It plays an important role in Vilsmeier formylation and glyoxylation reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

• CAS: 13498-14-1
• Molecular Weight (g/mol): 251.745
• InChI Key: CNTIXUGILVWVHR-UHFFFAOYSA-N
• PubChem CID: 4432411

• Molecular Formula: Cl4O3P2
• MDL Number: MFCD00061542
• Synonym: diphosphoryl chloride, pyrophosphoryl chloride, diphosphoryl tetrachloride, diphosphoric tetrachloride, pyrophosphoric tetrachloride, dichlorophosphoryl oxyphosphonoyl dichloride, pyrophosphoryl tetrachloride, pyrophosphorylchloride, phosphorodichloridic anhydride
• SMILES: O=P(OP(=O)(Cl)Cl)(Cl)Cl

Specifications

• Boiling Point: 101°C (10mmHg)
• CAS: 13498-14-1
• Physical Form: Liquid
• MDL Number: MFCD00061542
• Synonym: diphosphoryl chloride, pyrophosphoryl chloride, diphosphoryl tetrachloride, diphosphoric tetrachloride, pyrophosphoric tetrachloride, dichlorophosphoryl oxyphosphonoyl dichloride, pyrophosphoryl tetrachloride, pyrophosphorylchloride, phosphorodichloridic anhydride
• InChI Key: CNTIXUGILVWVHR-UHFFFAOYSA-N
• Molecular Weight (g/mol): 251.745
• Formula Weight: 251.76
• Sensitivity: Air & Moisture Sensitive
• Chemical Name or Material: Pyrophosphoryl chloride

• Melting Point: -17°C
• Color: Colorless through Yellow
• Molecular Formula: Cl4O3P2
• UN Number: UN3264
• Solubility Information: Reacts violently with waterMiscible with most organic solvents.
• SMILES: O=P(OP(=O)(Cl)Cl)(Cl)Cl
• PubChem CID: 4432411
• Odor: Acrid
• Density: 1.82g/mL

Safety and Handling

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

H314-H335

missing translation for 'dotInformation' : Hazard Class: 8; Packaging Group: I

missing translation for 'einecsNumber' : 236-824-4

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures; Store under Nitrogen

RUO – Research Use Only