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Phospho-MCL-1 (Ser159) Monoclonal Antibody (RBCERNR), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-9038-42
Code : NEW
Additional Details : Weight : 0.23750kg
Description
Mcl-1 (Myeloid cell leukemia-1) is a member of the bcl-2 family. The carboxy terminal of Mcl-1 and bcl-2 share significant sequence homology. Expression of Mcl-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g. ionizing radiation, ultraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in bcl-2. Enhanced expression of Mcl-1, prominently associated with mitochondria, complements the continued expression of bcl-2 in ML-1 cells undergoing differentiation. Like bcl-2, Mcl-1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis.
Phospho-MCL-1 (Ser159) Monoclonal antibody specifically detects Phospho-MCL-1 (Ser159) in Human, Mouse samples. It is validated for Flow Cytometry.Specifications
Phospho-MCL-1 (Ser159) | |
Monoclonal | |
5 μL/Test | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
P97287, Q07820 | |
MCL1 | |
Affinity chromatography | |
RUO | |
17210, 4170 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
RBCERNR | |
APC | |
MCL1 | |
AW556805; BCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; Bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Mcl1; Mcl-1; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; MCL-1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1; myeloid cell leukemia sequence 1 (BCL2-related); TM | |
Mouse | |
100 Tests | |
Primary | |
Human, Mouse | |
Antibody | |
IgG2b κ |
For Research Use Only.