Phorbol 12-Myristate 13-Acetate (Clear or Whitish Film), Fisher BioReagents™

Description

Phorbol 12-Myristate 13-Acetate (Clear or Whitish Film)

PMA is an activator of Protein Kinase C; it is a skin irritant and mouse skin tumor promoter.

Specifications

Chemical Identifiers

• CAS: 16561-29-8
• Molecular Formula: C36H56O8
• Molecular Weight (g/mol): 616.84
• MDL Number: MFCD00036736
• InChI Key: PHEDXBVPIONUQT-RGYGYFBISA-N
• Synonym: phorbol 12-myristate 13-acetate, phorbol ester, 12-o-tetradecanoylphorbol-13-acetate, 12-o-tetradecanoylphorbol 13-acetate, factor a1, tetradecanoylphorbol acetate, 12-tetradecanoylphorbol 13-acetate, factor a1 croton oil, phorbol 13-acetate 12-myristate, phorbol-12-myristate-13-acetate
• PubChem CID: 27924
• ChEBI: CHEBI:37537
• IUPAC Name: (1S,2S,6R,10S,11R,13S,14R,15R)-13-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0²,⁶.0¹¹,¹³]pentadeca-3,8-dien-14-yl tetradecanoate
• SMILES: CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(CO)=C[C@H]2[C@@H]2C(C)(C)[C@]12OC(C)=O

• Melting Point: 72°C
• Color: White
• Assay Percent Range: ≥99.0 %
• Packaging: Glass Ampule
• Quantity: 1 mg
• Formula Weight: 616.8
• Percent Purity: 99.0% min.
• Physical Form: Solid
• Chemical Name or Material: Phorbol 12-Myristate 13-Acetate

Safety and Handling

Product Identifier

• Phorbol 12-myristate 13-acetate

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H315-Causes skin irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.