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Thermo Scientific™ pH Gradient Buffers

Robust reproducible gradients that are applicable to a wide range of MAbs and ready to use with existing LC columns and systems, without the need to formulate mobile phases.

£138.00 - £2195.00

Specifications

For Use With (Equipment) LC Columns and Systems
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Products 15
Product Code Brand Description pH Quantity Price Quantity & Availability  
Product Code Brand Description pH Quantity Price Quantity & Availability  
15125624
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Thermo Scientific™
083273
CX-1 pH Gradient Buffer A 5.6 125 mL £138.00
125mL
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Estimated Shipment: 31-08-2021
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15135624
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Thermo Scientific™
083275
CX-1 pH Gradient Buffer B 10.2 125 mL £214.00
125mL
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Estimated Shipment: 23-09-2021
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15165624
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Thermo Scientific™
083274
CX-1 pH Gradient Buffer Kit;
125 mL Buffer A + 125 mL Buffer B
5.6 to 10.2 125 mL + 125 mL £252.00
125mL
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Estimated Shipment: 30-09-2021
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15145624
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Thermo Scientific™
085346
CX-1 pH Gradient Buffer A 5.6 250 mL £224.00
250mL
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Estimated Shipment: 31-08-2021
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15155624
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Thermo Scientific™
085348
CX-1 pH Gradient Buffer B 10.2 250 mL £226.00
250mL
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Estimated Shipment: 31-08-2021
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15121206
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Thermo Scientific™
085349
CX-1 pH Gradient Buffer Kit;
250 mL Buffer A + 250 mL Buffer B
5.6 to 10.2 250 mL + 250 mL £424.00
250mL
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Estimated Shipment: 31-08-2021
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15870452
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Thermo Scientific™
302779
CX-1 pH Gradient Buffer A £408.00
500mL
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Estimated Shipment: 27-08-2021
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15880452
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Thermo Scientific™
302780
CX-1 pH Gradient Buffer B £404.00
500mL
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Estimated Shipment: 27-08-2021
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15195624
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Thermo Scientific™
083381
CX-1 pH Gradient Starter Kit;
125 mL Buffer A + 125 mL Buffer B
MAbPac SCX-10 Column (10 µm, 4 x 250 mm)
5.6 to 10.2 125 mL + 125 mL
£949.00
125mL
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Estimated Shipment: 16-08-2021
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15185624
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Thermo Scientific™
083378
CX-1 pH Gradient High Throughput Kit;
125 mL Buffer A + 125 mL Buffer B
MAbPac SCX-10 Column (5 µm, 4 x 50 mm)
5.6 to 10.2 125 mL + 125 mL
£763.00
125mL
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Estimated Shipment: 16-08-2021
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15105634
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Thermo Scientific™
083272
CX-1 pH Gradient High Resolution Kit;
125 mL Buffer A + 125 mL Buffer B
MAbPac SCX-10 Column (5 µm, 4 x 250 mm)
5.6 to 10.2 125 mL + 125 mL
£1442.00
125mL
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Estimated Shipment: 16-08-2021
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15145634
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Thermo Scientific™
083270
CX-1 pH Gradient High Resolution Platform 5.6 to 10.2 125 mL This item is currently unavailable or has been discontinued.
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15135634
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Thermo Scientific™
083376
CX-1 pH Gradient High Throughput Platform 5.6 to 10.2 125 mL This item is currently unavailable or has been discontinued.
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15115634
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Thermo Scientific™
083380
CX-1 pH Gradient Starter Platform 5.6 to 10.2 125 mL This item is currently unavailable or has been discontinued.
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15105654
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Thermo Scientific™
085022
pH Designer Software This item is currently unavailable or has been discontinued.
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Description

Description

Obtain fast and highly robust, reproducible HPLC gradients using Thermo Scientific™ CX-1 pH Gradient Buffers. Simple to optimize and easily automated, these buffers are applicable for HPLC separation of the majority of monoclonal antibody (mAb) biotherapeutics drugs. CX-1 pH Gradient Buffers are ready to use with existing HPLC columns without the need to formulate mobile phases. The CX-1 buffers save time in method development, facilitate method transfer to QA/QC for a wide range of mAb charge variants through a generic HPLC-based approach to mAb characterization, and do not require time-consuming mobile phase adjustments.

pH buffer solutions can be used to generate highly reproducible, linear pH gradients in cation exchange chromatography.

  • Robust, reproducible gradients
  • Predict biomolecule pH
  • Simple method optimization
  • Easily automated
  • Applicable to the majority of MAbs

Unlike traditional cation exchange chromatography using salt gradients, it is possible to predict the pH and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation.

Specifications

Specifications

LC Columns and Systems
SDS
Product Certifications