P5CS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 17719-1-AP-20UL

Product Code. 16837664

Description

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Specifications

• Antigen: P5CS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALDH18A1
• Gene Alias: ALDH18A1, GK, GPR, GSAS, P5CS, PYCS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 361755, 56454, 5832
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunoprecipitation
• Concentration: 0.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P54886, Q9Z110
• Gene Symbols: Aldh18a1
• Immunogen: P5CS Fusion Protein Ag12100
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG