Thermo Scientific™ Opti-Link™ Carboxylate-Modified Particles

Control sensitivity, specificity and stability with various acid content available within Thermo Scientific™ Opti-Link™ Carboxylate-Modified Particles.

Product Code	Brand	Quantity	Diameter (Metric)	Surface Acid Loading	Concentration
11819922	Thermo Scientific™ 73003305100250	15 mL	2 μm	High Acid	10%
11829922	Thermo Scientific™ 73003305100350	100 mL	2 μm	High Acid	10%
11950085	Thermo Scientific™ 73003420100250	15 mL	3 μm	High Acid	10%
11960085	Thermo Scientific™ 73003420100350	100 mL	3 μm	High Acid	10%
12406462	Thermo Scientific™ 83000520100290	15 mL	0.2 μm	High Acid	10%
12416462	Thermo Scientific™ 83000520100390	100 mL	0.2 μm	High Acid	10%
12612550	Thermo Scientific™ 83000550100290	15 mL	0.2 μm	Medium Acid	10%
12446462	Thermo Scientific™ 83000550100390	100 mL	0.2 μm	Medium Acid	10%
11976558	Thermo Scientific™ 83000550100390	100 mL	0.2 μm	Medium Acid	10%
11894153	Thermo Scientific™ 83000720100290	15 mL	0.3 μm	High Acid	10%
11804163	Thermo Scientific™ 83000720100390	100 mL	0.3 μm	High Acid	10%
11814163	Thermo Scientific™ 83000750100290	15 mL	0.3 μm	Medium Acid	10%
11824163	Thermo Scientific™ 83000750100390	100 mL	0.3 μm	Medium Acid	10%
11834163	Thermo Scientific™ 83000920100290	15 mL	0.4 μm	High Acid	10%
11844163	Thermo Scientific™ 83000920100390	100 mL	0.4 μm	High Acid	10%
11894163	Thermo Scientific™ 83000970100290	15 mL	0.4 μm	Low Acid	10%
11804173	Thermo Scientific™ 83000970100390	100 mL	0.4 μm	Low Acid	10%
11814173	Thermo Scientific™ 83000970100490	1000 mL	0.4 μm	Low Acid	10%
11844203	Thermo Scientific™ 93000570100290	15 mL	0.2 μm	Low Acid	10%
11854203	Thermo Scientific™ 93000570100390	100 mL	0.2 μm	Low Acid	10%
11990075	Thermo Scientific™ W050CA	15 mL	0.5 μm	Medium Acid	4%
11900085	Thermo Scientific™ W050CB	100 mL	0.5 μm	Medium Acid	4%
11910085	Thermo Scientific™ W080CA	15 mL	0.85 μm	Medium Acid	4%
11920085	Thermo Scientific™ W080CB	100 mL	0.85 μm	Medium Acid	4%
11804962	Thermo Scientific™ W090CA	15 mL	0.9 μm	High Acid	4%
12493072	Thermo Scientific™ W090CB	100 mL	0.9 μm	High Acid	4%
11814962	Thermo Scientific™ W400CA	15 mL	4.0 μm	High Acid	4%
12433082	Thermo Scientific™ W400CB	100 mL	4.0 μm	High Acid	4%
11824962	Thermo Scientific™ W500CA	15 mL	5.0 μm	High Acid	4%
12453082	Thermo Scientific™ W500CB	100 mL	5.0 μm	High Acid	4%

Description

Control sensitivity, specificity and stability with various acid content available within Thermo Scientific™ Opti-Link™ Carboxylate-Modified Particles. Particles contain carboxylic acid groups for covalent coupling and can be used directly from the bottle in a variety of applications.

• Parking area combines surface area and acid content to give you the surface acid distribution that is useful for assay optimization
• Surface area per gram of a particle varies inversely with the particle diameter
• Acid content refers to the titrated milliequivalents per gram (mEq/g) and is weight-based
• For most applications, particles can be used directly from the bottle without any pre-cleaning
• Proprietary anionic surfactant does not interfere with binding of proteins nor cause proteins to desorb from particle surfaces or cause proteins to desorb from particle surfaces
• Various surface acid concentrations available to help optimize reagent development efforts
• Particles have been used in and are equally successful in molecular biology and research applications

Parking Area Properties

• Low Acid Content—60–100 Parking Area—Hydrophobic surface, more colloidally stable than plain polystyrene
• Medium Acid Content—35–59 Parking Area—Hydrophobic and hydrophilic areas; good colloidal stability and good covalent coupling
• High Acid Content—10–34 Parking Area—Hydrophilic surface; excellent colloidal stability; excellent covalent coupling

Recommended for:

• Clinical diagnostics
• Molecular biology
• Nephelometric, turbidimetric and slide agglutination assays

Note:

When using Opti-Link particles, ask about our Microparticle Reagent Optimization manual, which outlines our reagent development strategy. This manual includes validated binding, coupling and particle reagent optimization protocols.

Specifications

• Additive: Proprietary anionic surfactant
• Content And Storage: Unless otherwise stated, refrigerate (2° to 8°C) product when not in use but do not freeze. Store upright and keep bottle tightly sealed. Mix product with gentle inversion by hand or vortex mixer.
• For Use With (Application): Covalent Coupling
• Product Type: Specialty Particles
• Particle Density: 1.05g/cm³

• Certifications/Compliance: Includes Certificate of Analysis
• Description: Particles that contain carboxylic acid groups for covalent coupling and that can be used in a variety of applications.
• Material: Polystyrene Sulfate
• Includes: Package Insert Sheet containing Certicate of Analysis
• Specialty Packaging: Opti-Link Carboxylate-Modified Polystyrene particles are available in different concentrations and package sizes upon request.