O-Acetylsalicylic acid, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11458710	Thermo Scientific Alfa Aesar A12488.22	100 g
11454114	Thermo Scientific Alfa Aesar A12488.36	500 g
11464114	Thermo Scientific Alfa Aesar	2500 g

Description

O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

Solubility
Soluble in 100% ethanol (80mg/ml), DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS), pH 7.2 (2.7mg/ml).

Notes
Store at room temperature. Ensure good ventilation.

Chemical Identifiers

• CAS: 50-78-2
• Molecular Weight (g/mol): 180.16
• InChI Key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• PubChem CID: 2244
• IUPAC Name: 2-acetyloxybenzoic acid

• Molecular Formula: C9H8O4
• MDL Number: MFCD00002430
• Synonym: aspirin, acetylsalicylic acid, 2-acetoxybenzoic acid, 2-acetyloxy benzoic acid, acetylsalicylate, o-acetylsalicylic acid, o-acetoxybenzoic acid, acylpyrin, polopiryna, easprin
• ChEBI: CHEBI:15365
• SMILES: CC(=O)OC1=CC=CC=C1C(O)=O

Specifications

• CAS: 50-78-2
• Density: 1.4
• Molecular Formula: C9H8O4
• Beilstein: 779271
• Synonym: aspirin, acetylsalicylic acid, 2-acetoxybenzoic acid, 2-acetyloxy benzoic acid, acetylsalicylate, o-acetylsalicylic acid, o-acetoxybenzoic acid, acylpyrin, polopiryna, easprin
• InChI Key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• IUPAC Name: 2-acetyloxybenzoic acid
• PubChem CID: 2244
• Formula Weight: 180.15
• Chemical Name or Material: O-Acetylsalicylic acid

• Melting Point: 133°C to 140°C
• Flash Point: 250°C (482°F)
• MDL Number: MFCD00002430
• Merck Index: 14,851
• Solubility Information: Soluble in 100% ethanol (80mg/ml),DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS),pH 7.2 (2.7mg/ml).
• SMILES: CC(=O)OC1=CC=CC=C1C(O)=O
• Molecular Weight (g/mol): 180.16
• ChEBI: CHEBI:15365
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P264b-P270-P301+P312-P330-P501c

H302-H500

missing translation for 'einecsNumber' : 200-064-1

missing translation for 'rtecsNumber' : VO0700000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• O-Acetylsalicylic acid

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : O-Acetylsalicylic acid

RUO – Research Use Only