NR1H2 Mouse anti-Human, Porcine, Clone: 1E12B10, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 60345-1-IG-150UL

Product Code. 16897455

Description

LXR-B belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-A, LXR-B forms heterodimers with the retinoic acid receptor RXRalpha, which function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Other studies suggest that genetic variability at the LXR-B gene locus may be a risk factor for Alzheimer′s disease. One hypothesis postulates that LXR may be upstream of ApoE and potentiates the risk associated effects of the epsilon3 allele.

Specifications

• Antigen: NR1H2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P55055
• Gene Symbols: NR1H2
• Immunogen: NR1H2 Fusion Protein Ag5635
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Porcine
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 1E12B10
• Conjugate: Unconjugated
• Gene: NR1H2
• Gene Alias: Liver X receptor beta, LXR b, LXRB, NER, NER I, NR1H2, Nuclear receptor NER, Oxysterols receptor LXR beta, RIP15, UNR
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100525290, 7376
• Content And Storage: -20°C
• Form: Liquid