Nickel(II) chloride hexahydrate, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11466947	Thermo Scientific Alfa Aesar A14366.30	250 g
11456947	Thermo Scientific Alfa Aesar A14366.0B	1000 g
11476947	Thermo Scientific Alfa Aesar A14366.0I	5000 g

Description

Nickel(II) chloride is used in electroplating and as a catalyst for organic conversions, for example in chemo-selective thioacetalization of aldehydes. In combination with lithium aluminum hydride, it serves as a reducing agent for alkenes, alkynes, and organic halides; it can cleave N-O bond and open epoxides. It is used to prepare a wide array of complexes since water ligands can be easily replaced by amines, thioether, ammonia, and thiolates. It is a precursor to several nickel-phosphine complexes, such as bis(triphenylphosphine)nickel(II) chloride, which are used in alkyne trimerizations, carbonylations, and as catalysts in organic reactions such as Suzuki-Miyaura cross coupling reactions as an alternative to palladium(0) catalysts. It is the precursor to acetylacetonate complex of Ni, used for producing 1,5-cyclooctadiene complex, an important reagent in organonickel chemistry. It can be used to prepare the sandwich compound nickelocene through dimethoxyethane complex of nickel chloride.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nickel(II) chloride is used in electroplating and as a catalyst for organic conversions, for example in chemo-selective thioacetalization of aldehydes. In combination with lithium aluminum hydride, it serves as a reducing agent for alkenes, alkynes, and organic halides; it can cleave N-O bond and open epoxides. It is used to prepare a wide array of complexes since water ligands can be easily replaced by amines, thioether, ammonia, and thiolates. It is a precursor to several nickel-phosphine complexes, such as bis(triphenylphosphine)nickel(II) chloride, which are used in alkyne trimerizations, carbonylations, and as catalysts in organic reactions such as Suzuki-Miyaura cross coupling reactions as an alternative to palladium(0) catalysts. It is the precursor to acetylacetonate complex of Ni, used for producing 1,5-cyclooctadiene complex, an important reagent in organonickel chemistry. It can be used to prepare the sandwich compound nickelocene through dimethoxyethane complex of nickel chloride.

Notes
Store away from incompatible substances such as peroxides, strong acids and potassium.

Chemical Identifiers

• CAS: 7791-20-0
• Molecular Formula: Cl₂Ni·6H₂O
• MDL Number: MFCD00149809

Specifications

• Melting Point: 140°C (in 2H₂O)
• pH: 4.9
• Linear Formula: NiCl₂·6H₂O
• UN Number: UN3288
• Solubility Information: Freely soluble in water. Soluble in ethylene glycol,ethanol,and ammonium hydroxide.
• Percent Purity: 98%
• Density: 1.92

• CAS: 7791-20-0
• Molecular Formula: Cl₂Ni·6H₂O
• MDL Number: MFCD00149809
• Merck Index: 14,6505
• Formula Weight: 237.71 (129.60 Anhydrous)
• Odor: Odorless
• Chemical Name or Material: Nickel(II) chloride hexahydrate

Safety and Handling

GHS H Statement
H301-H331-H334-H350-H360-H372-H341-H315-H317
Toxic if swallowed.
Toxic if inhaled.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause cancer.
May damage fertility or the unborn child.
Causes damage to organs through prolonged or repeated exposure.
Suspected of causing genetic defects.
Causes skin irritation.
May cause an allergic skin reaction.

P201-P202-P260-P264b-P270-P271-P272-P280-P281-P285-P301+P310-P302+P352-P304+P340-P305+P351+P338-P308+P313-P311-P330-P333+P313-P362-P501c

H301+H331-H315-H317-H319-H334-H341-H350i-H360D-H372

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Recommended Storage : Ambient temperatures

Product Identifier

• Nickel(II) chloride hexahydrate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• LONG-TERM AQUATIC HAZARD Chronic 1
• ACUTE AQUATIC Acute 1
• Carcinogenicity Category 1A
• Germ cell mutagenicity Category 2
• Reproductive toxicity Category 1B
• Respiratory sensitiser Category 1
• Skin corrosion/irritation Category 2
• Skin sensitiser Category 1
• Specific target organ toxicity Category 1

Hazard Statement

• H301-Toxic if swallowed.
• H315-Causes skin irritation.
• H317-May cause an allergic skin reaction.
• H331-Toxic if inhaled.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H341-Suspected of causing genetic defects.
• H350i-May cause cancer by inhalation.
• H360D-May damage the unborn child.
• H372-Causes damage to organs.
• H400-Very toxic to aquatic life.
• H410-Very toxic to aquatic life with long lasting effects.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P273-Avoid release to the environment.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Nickel(II) chloridehexahydrate, Nickel(II) chloride

RUO – Research Use Only