N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide, 97%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11418780	Thermo Scientific Alfa Aesar B23760.03	1 g
11410208	Thermo Scientific Alfa Aesar B23760.06	5 g
11420208	Thermo Scientific Alfa Aesar B23760.14	25 g

Description

It finds its application in the preparation of N-tert-butyldimethylsilyl ethanolamines resulting from hydrolysis of nitrogen mustards and a silylating agent used in the derivatization of various organic compounds (such as amino acids) for gas chromatography-mass spectrometry (GC-MS) analysis and selective O-silylation of N,O-diacylhydroxylamines and GLC derivatization.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It finds its application in the preparation of N-tert-butyldimethylsilyl ethanolamines resulting from hydrolysis of nitrogen mustards and a silylating agent used in the derivatization of various organic compounds (such as amino acids) for gas chromatography-mass spectrometry (GC-MS) analysis and selective O-silylation of N,O-diacylhydroxylamines and GLC derivatization.

Solubility
Soluble in water (reacts).

Notes
Moisture sensitive. Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store away from electrostatic charges. Keep ignition sources away.

Chemical Identifiers

• CAS: 77377-52-7
• Molecular Weight (g/mol): 241.329
• InChI Key: QRKUHYFDBWGLHJ-UHFFFAOYSA-N
• PubChem CID: 2724275
• IUPAC Name: N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide

• Molecular Formula: C9H18F3NOSi
• MDL Number: MFCD00009671
• Synonym: mtbstfa, n-tert-butyldimethylsilyl-n-methyltrifluoroacetamide, n-methyl-n-tert-butyldimethylsilyl trifluoroacetamide, n-tert-butyldimethylsilyl-n-methyl-trifluoroacetamide, n-methyl-n-t-butyldimethylsilyl trifluoroacetamide, acetamide, n-1,1-dimethylethyl dimethylsilyl-2,2,2-trifluoro-n-methyl, n-t-butyldimethylsilyl-n-methyltrifluoroacetamide, n-t-butyldimethylsilyl-n-methyltrifluoro-acetamide
• ChEBI: CHEBI:85060
• SMILES: CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F

Specifications

• CAS: 77377-52-7
• Boiling Point: 168°C to 170°C
• Molecular Formula: C9H18F3NOSi
• MDL Number: MFCD00009671
• Beilstein: 3606546
• Synonym: mtbstfa, n-tert-butyldimethylsilyl-n-methyltrifluoroacetamide, n-methyl-n-tert-butyldimethylsilyl trifluoroacetamide, n-tert-butyldimethylsilyl-n-methyl-trifluoroacetamide, n-methyl-n-t-butyldimethylsilyl trifluoroacetamide, acetamide, n-1,1-dimethylethyl dimethylsilyl-2,2,2-trifluoro-n-methyl, n-t-butyldimethylsilyl-n-methyltrifluoroacetamide, n-t-butyldimethylsilyl-n-methyltrifluoro-acetamide
• InChI Key: QRKUHYFDBWGLHJ-UHFFFAOYSA-N
• IUPAC Name: N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
• PubChem CID: 2724275
• Formula Weight: 241.33
• Chemical Name or Material: N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide

• Density: 1.023
• Flash Point: 52°C (125°F)
• Refractive Index: 1.402
• UN Number: UN1993
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in water (reacts).
• SMILES: CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
• Molecular Weight (g/mol): 241.329
• ChEBI: CHEBI:85060
• Percent Purity: 97%

Safety and Handling

GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c

H226-H315-H319-H335

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missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

RUO – Research Use Only