N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11430033	Thermo Scientific Alfa Aesar A12107.09	10 g
11440033	Thermo Scientific Alfa Aesar A12107.18	50 g
11450033	Thermo Scientific Alfa Aesar A12107.30	250 g

Description

N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N,N′,N′-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

Solubility
Soluble in dimethyl sulfoxide, water and phosphate buffered saline at pH 7.2.

Notes
Light sensitive. Incompatible with strong oxidizing agents.                    

Chemical Identifiers

• CAS: 637-01-4
• Molecular Weight (g/mol): 237.168
• InChI Key: FBHKTSXMTASXFJ-UHFFFAOYSA-N
• PubChem CID: 71561
• SMILES: CN(C)C1=CC=C(C=C1)N(C)C.Cl.Cl

• Molecular Formula: C10H18Cl2N2
• MDL Number: MFCD00012482
• Synonym: n,n,n',n'-tetramethyl-p-phenylenediamine dihydrochloride, wurster's reagent dihydrochloride, n,n,n',n'-tetramethyl-1,4-phenylenediamine dihydrochloride, unii-66w8hka51x, n1,n1,n4,n4-tetramethylbenzene-1,4-diamine dihydrochloride, wurster's blue dihydrochloride, 1,4-benzenediamine, n,n,n',n'-tetramethyl-, dihydrochloride, 1,4-benzenediamine, n1,n1,n4,n4-tetramethyl-, hydrochloride 1:2, 1-n,1-n,4-n,4-n-tetramethylbenzene-1,4-diamine dihydrochloride, wursters reagent
• IUPAC Name: 1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine;dihydrochloride

Specifications

• CAS: 637-01-4
• Assay Percent Range: 99%
• MDL Number: MFCD00012482
• Sensitivity: Light sensitive
• Solubility Information: Soluble in dimethyl sulfoxide,water and phosphate buffered saline at pH 7.2.
• SMILES: CN(C)C1=CC=C(C=C1)N(C)C.Cl.Cl
• Molecular Weight (g/mol): 237.168
• Formula Weight: 237.17
• Chemical Name or Material: N,N,N',N'-Tetramethyl-p-phenylenediamine Dihydrochloride

• Melting Point: ∽228°C (decomposition)
• Molecular Formula: C10H18Cl2N2
• Beilstein: 5132096
• Synonym: n,n,n',n'-tetramethyl-p-phenylenediamine dihydrochloride, wurster's reagent dihydrochloride, n,n,n',n'-tetramethyl-1,4-phenylenediamine dihydrochloride, unii-66w8hka51x, n1,n1,n4,n4-tetramethylbenzene-1,4-diamine dihydrochloride, wurster's blue dihydrochloride, 1,4-benzenediamine, n,n,n',n'-tetramethyl-, dihydrochloride, 1,4-benzenediamine, n1,n1,n4,n4-tetramethyl-, hydrochloride 1:2, 1-n,1-n,4-n,4-n-tetramethylbenzene-1,4-diamine dihydrochloride, wursters reagent
• InChI Key: FBHKTSXMTASXFJ-UHFFFAOYSA-N
• IUPAC Name: 1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine;dihydrochloride
• PubChem CID: 71561
• Percent Purity: ≥98%

Safety and Handling

GHS H Statement
H315-H319-H335

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

missing translation for 'einecsNumber' : 211-274-8

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : N,N,N',N'-Tetramethyl-p-phenylenediaminedihydrochloride

RUO – Research Use Only