N,N-Dimethylacetamide, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11484313	Thermo Scientific Alfa Aesar A10924.AP	500 mL
11494313	Thermo Scientific Alfa Aesar A10924.0F	2500 mL

Description

N,N-Dimethylacetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide. It is also used as a solvent for fibers like polyacrylonitrile, spandex, as an excipient in drugs viz. vumon, busulfex and in the adhesive industry. It finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers. It is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins. It plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products. It is also used as an extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N-Dimethylacetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide. It is also used as a solvent for fibers like polyacrylonitrile, spandex, as an excipient in drugs viz. vumon, busulfex and in the adhesive industry. It finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers. It is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins. It plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products. It is also used as an extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.

Solubility
Miscible with water, benzene, alcohol, acetone, ether, esters and ketones.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

Chemical Identifiers

• CAS: 127-19-5
• Molecular Weight (g/mol): 87.12
• InChI Key: FXHOOIRPVKKKFG-UHFFFAOYSA-N
• PubChem CID: 31374
• IUPAC Name: N,N-dimethylacetamide

• Molecular Formula: C4H9NO
• MDL Number: MFCD00008686
• Synonym: dimethylacetamide, dmac, acetamide, n,n-dimethyl, acetdimethylamide, dimethyl acetamide, n,n-dimethyl acetamide, dimethylamide acetate, n,n-dimethylethanamide, dimethylacetone amide, acetyldimethylamine
• ChEBI: CHEBI:84254
• SMILES: CN(C)C(C)=O

Specifications

• CAS: 127-19-5
• Density: 0.94
• Flash Point: 70°C (158°F)
• Molecular Formula: C4H9NO
• Refractive Index: 1.4385
• Beilstein: 1737614
• Synonym: dimethylacetamide, dmac, acetamide, n,n-dimethyl, acetdimethylamide, dimethyl acetamide, n,n-dimethyl acetamide, dimethylamide acetate, n,n-dimethylethanamide, dimethylacetone amide, acetyldimethylamine
• InChI Key: FXHOOIRPVKKKFG-UHFFFAOYSA-N
• IUPAC Name: N,N-dimethylacetamide
• PubChem CID: 31374
• Formula Weight: 87.12
• Chemical Name or Material: N,N-Dimethylacetamide

• Melting Point: -20°C
• Boiling Point: 165°C to 166°C
• Odor: Ammonia-like
• Linear Formula: CH₃CON(CH₃)₂
• MDL Number: MFCD00008686
• Merck Index: 14,3227
• Solubility Information: Miscible with water,benzene,alcohol,acetone,ether,esters and ketones.
• SMILES: CN(C)C(C)=O
• Molecular Weight (g/mol): 87.12
• ChEBI: CHEBI:84254
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H360-H312-H332-H227
May damage fertility or the unborn child.
Harmful in contact with skin.
Harmful if inhaled.
Combustible liquid.

P201-P202-P210-P261-P271-P281-P302+P352-P304+P340-P308+P313-P312-P363-P370+P378q-P501c

H227-H312+H332-H360D

missing translation for 'dotInformation' : Hazard Class: 6.1; Packaging Group: III

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missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• N,N-Dimethylacetamide

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Reproductive toxicity Category 1B

Hazard Statement

• H312-Harmful in contact with skin.
• H319-Causes serious eye irritation.
• H332-Harmful if inhaled.
• H360D-May damage the unborn child.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : N,N-Dimethylacetamide

RUO – Research Use Only