Methoxycarbonylsulfenyl chloride, 95%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11376896	Thermo Scientific Alfa Aesar L04350.03	1 g
11386896	Thermo Scientific Alfa Aesar L04350.06	5 g

Description

Methoxycarbonylsulfenyl chloride is used to prepare 3-[(methoxycarbonyl)dithio]-L-alanine by reacting with L-cysteine. Further, it is used in the synthesis of 3-2 pyridinyldithio propanoic acid hydrazide (PDPH). It serves as an important heterobifunctional crosslinker, which is a crosslinker used to make macromolecule-drug conjugates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methoxycarbonylsulfenyl chloride is used to prepare 3-[(methoxycarbonyl)dithio]-L-alanine by reacting with L-cysteine. Further, it is used in the synthesis of 3-2 pyridinyldithio propanoic acid hydrazide (PDPH). It serves as an important heterobifunctional crosslinker, which is a crosslinker used to make macromolecule-drug conjugates.

Solubility
Miscible with dichlormethane.

Notes
Moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Chemical Identifiers

• CAS: 26555-40-8
• Molecular Weight (g/mol): 126.554
• InChI Key: TXJXPZVVSLAQOQ-UHFFFAOYSA-N
• PubChem CID: 123417
• SMILES: COC(=O)SCl

• Molecular Formula: C2H3ClO2S
• MDL Number: MFCD00013648
• Synonym: methoxycarbonylsulfenyl chloride, methoxycarbonyl sulfenyl chloride, s-chloro o-methyl thiocarbonate, thiocarbonic acid, anhydrosulphide with methyl thiohypochlorite, carbonothioic acid, anhydrosulfide with thiohypochlorous acid, methyl ester, acmc-209gs8, methoxycarbonylsulfenylchloride, chlorothio methoxy oxomethane, methoxy carbonylsulfenyl chloride, methoxy-carbonylsulfenyl chloride
• IUPAC Name: methyl chlorosulfanylformate

Specifications

• CAS: 26555-40-8
• Boiling Point: 73°C to 74°C (100 mmHg)
• Molecular Formula: C2H3ClO2S
• MDL Number: MFCD00013648
• Beilstein: 1849908
• Synonym: methoxycarbonylsulfenyl chloride, methoxycarbonyl sulfenyl chloride, s-chloro o-methyl thiocarbonate, thiocarbonic acid, anhydrosulphide with methyl thiohypochlorite, carbonothioic acid, anhydrosulfide with thiohypochlorous acid, methyl ester, acmc-209gs8, methoxycarbonylsulfenylchloride, chlorothio methoxy oxomethane, methoxy carbonylsulfenyl chloride, methoxy-carbonylsulfenyl chloride
• InChI Key: TXJXPZVVSLAQOQ-UHFFFAOYSA-N
• IUPAC Name: methyl chlorosulfanylformate
• PubChem CID: 123417
• Percent Purity: 95%

• Density: 1.398
• Flash Point: 54°C (129°F)
• Refractive Index: 1.482
• UN Number: UN2920
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with dichlormethane.
• SMILES: COC(=O)SCl
• Molecular Weight (g/mol): 126.554
• Formula Weight: 126.56
• Chemical Name or Material: Methoxycarbonylsulfenyl chloride

Safety and Handling

GHS H Statement
H314-H318-H226
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.

P210-P233-P240-P241-P242-P243-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

H226-H314

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missing translation for 'tsca' : No

Recommended Storage : Keep cold

RUO – Research Use Only