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MED14 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA566666
Additional Details : Weight : 0.01000kg
Description
Immunogen sequence: PIAPPGTPAVV LKSKMLFFLQ LTQKTSVPPQ EPVSIIVPII YDMASGTTQQ ADIPRQQNSS VAAPMMVSNI LKRFAEMNP Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.Specifications
MED14 | |
Polyclonal | |
Unconjugated | |
Med14 | |
9930001L01Rik; Activator-recruited cofactor 150 kDa component; ARC150; AU041628; Cofactor required for Sp1 transcriptional activation subunit 2; cofactor required for Sp1 transcriptional activation subunit 2 (150 kDa); cofactor required for Sp1 transcriptional activation, subunit 2; cofactor required for Sp1 transcriptional activation, subunit 2 (150kD); CRSP complex subunit 2; CRSP150; CRSP2; CSRP; CXorf4; DRIP150; ENSMUSG00000073278; EXLM1; Gm641; hRGR1; human homolog of yeast RGR1; MED14; Mediator complex subunit 14; mediator of RNA polymerase II transcription subunit 14; MGC104513; ORF1; RGD1560170; RGR1; RGR1 homolog; thyroid hormone receptor-associated protein complex 170 kDa component; thyroid hormone receptor-associated protein complex component TRAP170; Transcriptional coactivator CRSP150; transcriptional co-activator CRSP150; TRAP170; vitamin D receptor-interacting protein complex component DRIP150; vitamin D3 receptor-interacting protein complex 150 kDa component | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
9282 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O60244 | |
Med14 | |
Recombinant Human MED14 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
For Research Use Only