(±)-Mandelic Acid, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11452327	Thermo Scientific Alfa Aesar A14223.22	100 g
11462327	Thermo Scientific Alfa Aesar A14223.36	500 g
11472327	Thermo Scientific Alfa Aesar A14223.0E	2500 g

Description

Mandelic acid is used in the pharmaceutical industry as an antibacterial to treat urinary tract infections. It acts as a precursor for making various drugs. It is also used as an oral antibiotic. Mandelic acid peels are widely used for treating damaged skin due to its less penetrating and irritating property. Enantiomeric resolution of (±)-Mandelic acid is performed by using the chiral amine (1R,2S)-(-)-ephedrine followed by acidification to prepare (R)-( -)-Mandelic acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Mandelic acid is used in the pharmaceutical industry as an antibacterial to treat urinary tract infections. It acts as a precursor for making various drugs. It is also used as an oral antibiotic. Mandelic acid peels are widely used for treating damaged skin due to its less penetrating and irritating property. Enantiomeric resolution of (±)-Mandelic acid is performed by using the chiral amine (1R,2S)-(-)-ephedrine followed by acidification to prepare (R)-( -)-Mandelic acid.

Solubility
Soluble in water, diethyl ether, ethanol and isopropanol.

Notes
Hydrophobic and light sensitive. Incompatible with strong oxidizing agents and reducing agents.

Chemical Identifiers

• CAS: 90-64-2
• Molecular Weight (g/mol): 152.149
• InChI Key: IWYDHOAUDWTVEP-UHFFFAOYSA-N
• PubChem CID: 1292
• IUPAC Name: 2-hydroxy-2-phenylacetic acid

• Molecular Formula: C8H8O3
• MDL Number: MFCD00064250
• Synonym: mandelic acid, dl-mandelic acid, phenylglycolic acid, amygdalic acid, almond acid, uromaline, p-mandelic acid, racemic mandelic acid, paramandelic acid, rs-mandelic acid
• ChEBI: CHEBI:35825
• SMILES: C1=CC=C(C=C1)C(C(=O)O)O

Specifications

• CAS: 90-64-2
• Assay Percent Range: 99%
• MDL Number: MFCD00064250
• Merck Index: 14,5717
• Solubility Information: Soluble in water,diethyl ether,ethanol and isopropanol.
• SMILES: C1=CC=C(C=C1)C(C(=O)O)O
• Molecular Weight (g/mol): 152.149
• ChEBI: CHEBI:35825
• Percent Purity: 99%
• Chemical Name or Material: (±)-Mandelic Acid

• Melting Point: 118°C to 121°C
• Molecular Formula: C8H8O3
• Beilstein: 510011
• Synonym: mandelic acid, dl-mandelic acid, phenylglycolic acid, amygdalic acid, almond acid, uromaline, p-mandelic acid, racemic mandelic acid, paramandelic acid, rs-mandelic acid
• InChI Key: IWYDHOAUDWTVEP-UHFFFAOYSA-N
• IUPAC Name: 2-hydroxy-2-phenylacetic acid
• PubChem CID: 1292
• Formula Weight: 152.15
• Sensitivity: Light sensitive

Safety and Handling

GHS H Statement
H318

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302-H315-H319-H335

missing translation for 'einecsNumber' : 202-007-6

missing translation for 'rtecsNumber' : OO6300000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• DL-Mandelic acid

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : .alpha.-hydroxy-Benzeneacetic acid

RUO – Research Use Only