Invitrogen™ LRRK2 [D1994A] Human Protein

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Certain mutations (e.g. I2020T, G2019S, and R1441C) in this gene have been associated with Parkinson 's disease.

Brand:  Invitrogen™ PV6052

Product Code. 15498803

Description

D1994A is an artificial mutation that renders the kinase catalytically inactive and thus serves as a useful control for activity assays, especially when testing novel substrates.

Specifications

• Accession Number: NP_940980.2
• Molecular Weight (g/mol): 205kDa
• Storage Requirements: Kinase proteins are shipped on dry ice and should be stored at -80°C.
• Structural Form: Catalytic
• KinaseFamily: LRRK Kinase Family
• Protein Tag: GST Tag
• Form: Frozen

• For Use With (Application): Enzyme and Protein Activity Assay, Kinase Assay, Protein Assays and Analysis, Protein Biology
• Quantity: 1 mg
• Regulatory Status: RUO - research use only
• Gene Alias: LRRK2 D1994A
• Species: Human
• Expression System: Baculovirus