Invitrogen™ LOX-1/OLR Human ELISA Kit

Sandwich ELISA Kit

Product Code	Brand	Quantity
15425093	Invitrogen™ EHOLR1	96 Tests
17155529	Invitrogen™ EHOLR1X5	5 x 96 Tests

Description

The Human LOX-1 (OLR) ELISA quantitates Hu LOX-1 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu LOX-1. Principle of the method The Human LOX-1 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Specifications

• Accession Number: P78380
• Assay: Solid-phase sandwich ELISA
• Product Type: ELISA Kit
• Sample Type: Plasma, Serum, Supernatant
• Target Species: Human
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene Symbol: CLEC8A,LOX1,LOXIN,SCARE1,SLOX1
• Intraassay CV: <10%
• Regulatory Status: RUO
• Storage Requirements: 2°C to 8°C
• Target: Human
• Total Assay Time: 4 hr. 45 min.

• Assay Sensitivity: 2 pg/mL
• Conjugate: Biotin
• Protein Family: Cell Structure & Organelle Proteins
• Specificity: This ELISA pair antibody detects human LOX-1. Other species not determined yet.
• For Use With (Application): ELISA, Protein Assays, Protein Biology, Cancer Biology, Immunology, Neuroscience, Neurobiology, Protein Detection, Protein Analysis
• Gene ID (Entrez): 4973
• Interassay CV: <12%
• Label or Dye: HRP
• Research Discipline: Extracellular Matrix & Cell Adhesion
• Synonym: CLEC8A, LOX1, LOXIN, SCARE1, SLOX1
• Test Time: 1 hr. 20 min.