HOXA5 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA550045

Product Code. 15663975

Description

The antibody detects endogenous levels of total HOXA5 protein. This antibody detects HoxA5 in cervical neuromesodermal progenitors.

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Specifications

• Antigen: HOXA5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXA5
• Gene Alias: homeo box 1C; homeo box A5; homeobox A5; homeobox protein Hox-1.3; Homeobox protein Hox-1C; homeobox protein HOXA5; homeobox protein Hox-A5; homeobox protein M2; HOX1; HOX1.3; Hox-1.3; HOX1C; Hox-1C; Hoxa5; Hoxa-5; Unknown (protein for MGC:138007)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15402, 3202, 79241
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P09021, P20719, P52949
• Gene Symbols: HOXA5
• Immunogen: Synthesized peptide derived from N-terminal of human HXA5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG