HOMER3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA559383

Product Code. 15747241

Description

Immunogen sequence: ALVQTKDQEI QTLKSQTGGP REALEAAERE ETQQKVQDLE TRNAELEHQL RAMERSLEEA RAERERARAE VGRAAQLLDV RLFELSELRE GL Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 88%.

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: HOMER3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOMER3
• Gene Alias: AW146114; homer homolog 3; homer homolog 3 (Drosophila); homer protein homolog 3; homer scaffolding protein 3; Homer, neuronal immediate early gene, 3; HOMER3; homer-3; VASP/Ena-related gene up-regulated during seizure and LTP 3; Vesl3; Vesl-3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9454
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NSC5
• Gene Symbols: HOMER3
• Immunogen: Recombinant protein corresponding to Human HOMER3
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only