Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns

Designed for method optimization and parameter screening for capture of monoclonal antibodies. Cytiva HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns come ready-to-use for convenience.

Brand:  Cytiva 17-5474-15

Product Code. 11603084

Description

• Ready-to-use columns for convenient process development
• Rigid, highly cross-linked agarose matrix
• Bed height of 10cm is designed to allow method optimization and parameter screening
• Easily connected in series to achieve 20cm bed height
• Small bed volume (4.7mL) gives fast result and minimal sample/buffer consumption
• Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity

MabSelect

• For capture of MAbs from large sample volumes
• Prepacked with protein A-derived media
• Compatible with high flow rates and high pressure when scaling up

MabSelect Xtra

• Increased binding capacity enables purification of MAbs from high-level expression feedstock
• Also optimized for Fc-fusion proteins
• Very low, unspecific binding due to high ligand selectivity and matrix hydrophilicity
• Prepacked with protein A-derived media

MabSelect SuRe (Superior Resistance) and MabSelect SuRe (Superior Resistance) LX

• With novel, alkali-tolerant recombinant protein A ligand that provides greater stability and allows use of 0.1 to 0.5M sodium hydroxide for cleaning-in-place (CIP)
• Enhanced protease resistance resulting in lower ligand leakage
• High dynamic binding capacity

Specifications

• Buffer: 8M Urea, 6M Guanidine Hydrochloride, 2% Benzyl Alcohol or 20% Ethanol
• Includes: Stoppers at the inlet and outlet
• Bed Support: Filter
• Binding Capacity: ≈60mg Human IgG
• Product Type: HiScreen MabSelect SuRe LX Prepacked Column
• Height (Metric) Bed: 10cm
• Ligand: Alkali-stabilized Protein A-derived (E. coli)
• Material: Polypropylene
• Max. Pressure: 3bar
• Storage Requirements: 2° to 8°C

• Column Type: HiScreen MabSelect SuRe LX Prepacked Column
• Kit Size: 1 x 4.7mL
• Diameter (English) Inner: 0.3 in.
• Diameter (Metric) Inner: 0.77cm
• Height (English) Bed: 3.93 in.
• For Use With (Application): Designed for method optimization and parameter screening for capture of monoclonal antibodies
• Ligand Coupling Method: Epoxy Activation
• Particle Size: 85μm
• pH: 3 to 12
• Format: Column

Safety and Handling

Product Identifier

• HiScreen MabSelect SuRe LX

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3

Hazard Statement

• H226-Flammable liquid and vapour.

Precautionary Statement

• P240-Ground/bond container and receiving equipment.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : ethanol
• UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.