Hexamethyldisilazane, 98+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11492108	Thermo Scientific Alfa Aesar A15139.AE	100 mL
11402118	Thermo Scientific Alfa Aesar A15139.AP	500 mL
11412118	Thermo Scientific Alfa Aesar A15139.0F	2500 mL

Description

Hexamethyldisilazane is used as a solvent in organic synthesis and organometallic chemistry. It is often used as an adhesion promoter for photoresist in photolithography. Further, it is used for the preparation of trimethylsilyl ethers from hydroxy compounds. It is used as an alternative to critical point drying during sample preparation in electron microscopy. It is added to analyte to get silylated diagnostic products during pyrolysis in gas chromatography- mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Hexamethyldisilazane is used as a solvent in organic synthesis and organometallic chemistry. It is often used as an adhesion promoter for photoresist in photolithography. Further, it is used for the preparation of trimethylsilyl ethers from hydroxy compounds. It is used as an alternative to critical point drying during sample preparation in electron microscopy. It is added to analyte to get silylated diagnostic products during pyrolysis in gas chromatography- mass spectrometry.

Solubility
Miscible with methanol, chloroform, ethyl ether and benzene. Immiscible with water.                    

Notes
Incompatible with strong oxidizing agents and strong acids.  

Chemical Identifiers

• CAS: 999-97-3
• Molecular Weight (g/mol): 161.395
• InChI Key: FFUAGWLWBBFQJT-UHFFFAOYSA-N
• PubChem CID: 13838
• IUPAC Name: [dimethyl-(trimethylsilylamino)silyl]methane

• Molecular Formula: C6H19NSi2
• MDL Number: MFCD00008259
• Synonym: hexamethyldisilazane, bis trimethylsilyl amine, hmds, 1,1,1,3,3,3-hexamethyldisilazane, hexamethylsilazane, silanamine, 1,1,1-trimethyl-n-trimethylsilyl, tri-sil, 1,1,1-trimethyl-n-trimethylsilyl silanamine, hexamethyldisilizane, disilazane, 1,1,1,3,3,3-hexamethyl
• ChEBI: CHEBI:85068
• SMILES: C[Si](C)(C)N[Si](C)(C)C

Specifications

• CAS: 999-97-3
• Density: 0.774
• Flash Point: 8°C (46°F)
• Odor: Odorless
• Linear Formula: (CH₃)₃SiNHSi(CH₃)₃
• MDL Number: MFCD00008259
• Beilstein: 635752
• Merck Index: 14,4689
• Solubility Information: Miscible with methanol,chloroform,ethyl ether and benzene. Immiscible with water.
• SMILES: C[Si](C)(C)N[Si](C)(C)C
• Molecular Weight (g/mol): 161.395
• ChEBI: CHEBI:85068
• Percent Purity: ≥98%
• Chemical Name or Material: Hexamethyldisilazane

• Melting Point: -78°C
• Boiling Point: 126°C
• Assay Percent Range: 98+%
• Molecular Formula: C6H19NSi2
• Refractive Index: 1.408
• UN Number: UN3286
• Sensitivity: Moisture sensitive
• Synonym: hexamethyldisilazane, bis trimethylsilyl amine, hmds, 1,1,1,3,3,3-hexamethyldisilazane, hexamethylsilazane, silanamine, 1,1,1-trimethyl-n-trimethylsilyl, tri-sil, 1,1,1-trimethyl-n-trimethylsilyl silanamine, hexamethyldisilizane, disilazane, 1,1,1,3,3,3-hexamethyl
• InChI Key: FFUAGWLWBBFQJT-UHFFFAOYSA-N
• IUPAC Name: [dimethyl-(trimethylsilylamino)silyl]methane
• PubChem CID: 13838
• Formula Weight: 161.4
• Physical Form: Liquid

Safety and Handling

GHS H Statement
H225-H311-H331-H314-H318-H302
Highly flammable liquid and vapour.
Toxic in contact with skin.
Toxic if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.

P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

H225-H302+H332-H311-H314-H335

missing translation for 'dotInformation' : Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUID, TOXIC, CORROSIVE, N.O.S.

missing translation for 'einecsNumber' : 213-668-5

missing translation for 'rtecsNumber' : JM9230000

missing translation for 'tsca' : Yes

missing translation for 'storageNote' : Moisture sensitive

Recommended Storage : Ambient temperatures; Store under Nitrogen

Product Identifier

• Hexamethyldisilazane

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• LONG-TERM AQUATIC HAZARD Chronic 3
• Flammable liquid Category 2

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H302-Harmful if swallowed.
• H311-Toxic in contact with skin.
• H332-Harmful if inhaled.
• H412-Harmful to aquatic life with long lasting effects.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : Hexamethyldisilazane

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RUO – Research Use Only