FOXC1 Mouse anti-Human, Clone: 1F4E11, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66568-1-IG-20UL

Product Code. 16848565

Description

FOXC1 is a protein belonging to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this protein is not known, however, it plays a role in the regulation of FGF19-FGFR4-MAPK pathway to promote both the development and maintece of anterior segment structures within the eye. Mutations in this gene cause various glaucoma, iridogoniodysgenesis anomaly, Peters anomaly that includes central corneal leukoma, absence of the posterior corneal stroma and Descemetmembrane and Axenfeld-Rieger anomaly characterized by posterior corneal embryotoxon, iris adhesion to the Schwalbe line, hypertelorism, hypoplasia of the malar bones, congenital absence of some teeth and mental retardation.

Specifications

• Antigen: FOXC1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q12948
• Gene Symbols: FOXC1
• Immunogen: Peptide
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 1F4E11
• Conjugate: Unconjugated
• Gene: FOXC1
• Gene Alias: ARA, FKHL7, forkhead box C1, Forkhead box protein C1, Forkhead related protein FKHL7, FOXC1, FREAC 3, FREAC3, IGDA, IHG1, IRID1, RIEG3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 2296
• Content And Storage: -20°C
• Form: Liquid