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Thermo Scientific™ 5-Fluoroorotic Acid
Detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase with Thermo Scientific™ 5-Fluoroorotic Acid, used in yeast molecular genetics.
£88.75 - £368.00
Specifications
| Chemical Name or Material | 5-Fluoroorotic Acid |
|---|---|
| Product Type | 5-Fluoroorotic Acid |
| Form | Powder |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
10609920
|
Thermo Scientific™
R0811 |
1 g |
£88.75
1g |
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|
10619920
|
Thermo Scientific™
R0812 |
5 g |
£368.00
5g |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
5-Fluoroorotic Acid is a yeast with an active URA3 gene (Ura+) converts 5-FOA to fluorodeoxyuridine, which is toxic to cells (see the scheme below). Yeast strains carrying a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil. 5-FOA is frequently used in experiments with Saccharomyces cerevisiae (URA3), Schizosaccharomyces pombe (URA4 and URA5), Candida albicans (URA3), and E. coli (pyrF).
Convertion of 5-FOA to fluorodeoxyuridine
Convertion of 5-FOA to fluorodeoxyuridine
Specifications
| 5-Fluoroorotic Acid | |
| 5-Fluoroorotic Acid | |
| Powder |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- 5-Fluoroorotic acid monohydrate
Signal Word
- Warning
Hazard Category
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H302-Harmful if swallowed.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
Supplemental information
- MIXTURE LIST-Contains : 5-Fluoroorotic acidmonohydrate
For Research Use Only. Not for use in diagnostic procedures.
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