Ethyl glyoxylate, ca 50% soln. in toluene, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11344076	Thermo Scientific Alfa Aesar L19207.22	100 g
11354076	Thermo Scientific Alfa Aesar L19207.36	500 g

Description

Ethyl glyoxylate is widely used as an intermediate in the synthesis of pharmaceuticals (high reactivity of aldehyde function). It is used in the synthesis of a biodegradable polymer, poly(ethyl glyoxylate). It is actively involved in the Friedel-Crafts alkylation reactions with thiophenes to give the corresponding secondary alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl glyoxylate is widely used as an intermediate in the synthesis of pharmaceuticals (high reactivity of aldehyde function). It is used in the synthesis of a biodegradable polymer, poly(ethyl glyoxylate). It is actively involved in the Friedel-Crafts alkylation reactions with thiophenes to give the corresponding secondary alcohols.

Solubility
Immiscible with water.

Notes
Air sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Chemical Identifiers

• CAS: 924-44-7
• Molecular Weight (g/mol): 102.089
• InChI Key: DBPFRRFGLYGEJI-UHFFFAOYSA-N
• PubChem CID: 70211
• IUPAC Name: ethyl 2-oxoacetate

• Molecular Formula: C4H6O3
• MDL Number: MFCD00044009
• Synonym: ethyl glyoxalate, ethyl glyoxylate, ethyl oxoacetate, glyoxylic acid ethyl ester, acetic acid, oxo-, ethyl ester, ethyl glyoxalate solution, unii-ixx9mq1j1i, acetic acid, 2-oxo-, ethyl ester, ixx9mq1j1i, 2-oxoacetic acid, ethyl ester
• ChEBI: CHEBI:53275
• SMILES: CCOC(=O)C=O

Specifications

• CAS: 924-44-7
• Boiling Point: 110°C
• Molecular Formula: C4H6O3
• MDL Number: MFCD00044009
• Beilstein: 1209486
• Synonym: ethyl glyoxalate, ethyl glyoxylate, ethyl oxoacetate, glyoxylic acid ethyl ester, acetic acid, oxo-, ethyl ester, ethyl glyoxalate solution, unii-ixx9mq1j1i, acetic acid, 2-oxo-, ethyl ester, ixx9mq1j1i, 2-oxoacetic acid, ethyl ester
• InChI Key: DBPFRRFGLYGEJI-UHFFFAOYSA-N
• IUPAC Name: ethyl 2-oxoacetate
• PubChem CID: 70211
• Formula Weight: 102.09
• Chemical Name or Material: Ethyl glyoxylate

• Density: 1.003
• Flash Point: 7°C (44°F)
• Refractive Index: 1.475
• UN Number: UN1993
• Sensitivity: Air Sensitive
• Solubility Information: Immiscible with water.
• SMILES: CCOC(=O)C=O
• Molecular Weight (g/mol): 102.089
• ChEBI: CHEBI:53275
• Concentration or Composition (by Analyte or Components): ≈50% soln. in toluene

Safety and Handling

GHS H Statement
H225-H304-H361-H373-H315-H336
Highly flammable liquid and vapor.
May be fatal if swallowed and enters airways.
Suspected of damaging fertility or the unborn child.
May cause damage to organs through prolonged or repeated exposure.
Causes skin irritation.
May cause drowsiness or dizziness.

P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P272-P280-P281-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P331-P333+P313-P363-P370+P378q-P501c

H225-H304-H315-H317-H319-H335-H336-H361d-H373

missing translation for 'dotInformation' : Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.

missing translation for 'einecsNumber' : 213-105-3

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier

• Ethyl glyoxylate, ca 50% solution in toluene

Signal Word

• Danger

Hazard Category

• Aspiration toxicity Category 1
• Flammable liquid Category 2
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 2
• Skin sensitiser Category 1
• Specific target organ toxicity after repeated exposure Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H304-May be fatal if swallowed and enters airways.
• H315-Causes skin irritation.
• H317-May cause an allergic skin reaction.
• H336-May cause drowsiness or dizziness.
• H361d-Suspected of damaging the unborn child.
• H373-May cause damage to organs.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P240-Ground/bond container and receiving equipment.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Supplemental information

• MIXTURE LIST-Contains : toluene, oxo-aceticacid

RUO – Research Use Only