COX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12375-1-AP-20UL

Product Code. 16850064

Description

PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

Specifications

• Antigen: COX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTGS2
• Gene Alias: COX 2, COX2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19225, 29527, 5743
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
• Concentration: 0.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P35354, P35355, Q05769
• Gene Symbols: PTGS2
• Immunogen: COX2 Fusion Protein Ag3025
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human, Rat
• Product Type: Antibody
• Isotype: IgG