Chromomycin A3, 97%, Thermo Scientific Chemicals

Description

 

Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of the transcription factors Sp1 and Sp3 to their cognate G-C box, induced by oxidative stress or DNA damage. Furthermore, by inhibiting transcription, Chromomycin A3 and its structural analogs can inhibit protein biosynthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced DNA binding of the transcription factors Sp1 and Sp3 to their cognate ″G-C&Pr

Specifications

• Type: Chromomycin A3
• Physical Form: Powder
• CAS: 7059-24-7
• Melting Point: 185°C (decomposition)
• Color: Yellow
• Quantity: 10 mg
• Molecular Formula: C57H82O26
• MDL Number: MFCD00043151
• UN Number: UN3462
• Merck Index: 14,2238
• Solubility Information: Soluble in ethanol,DMSO,and ethyl acetate (10mg/ml).
• InChI Key: ZYVSOIYQKUDENJ-YVQLHGKOSA-N
• SMILES: CC1C(C(CC(O1)OC2C(CC3=C(C2=O)C(=C4C(=C3)C=C(C(=C4O)C)OC5CC(C(C(O5)C)OC(=O)C)OC6CC(C(C(O6)C)OC)O)O)C(C(=O)C(C(C)O)O)OC)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)OC(=O)C)(C)O)O
• IUPAC Name: [(2R,3R,4R,6S)-6-[[(6S,7S)-6-[(2S,4R,5R,6R)-4-[(4R,5S,6R)-4-[(2S,4S,5R,6R)-5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-7-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-4,10-dihydroxy-3-
• Molecular Weight (g/mol): 1183.257
• PubChem CID: 23928042
• Formula Weight: 1183.3
• Percent Purity: 97%
• Chemical Name or Material: Chromomycin A3

RUO – Research Use Only