Carbenicillin disodium salt, Thermo Scientific Chemicals

Description

Carbenicillin disodium salt, CAS # 4800-94-6, is the disodium salt form of carbenicillin, a semisynthetic compound with broad-spectrum antibacterial and β-lactamase-resistant activities.

Carbenicillin disodium salt is a water-soluble antibiotic which is effective against gram-negative bacteria.Carbenicillin disodium salt is widely utilized as an antibiotic which is used to control bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. It has been involved in the study of the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Carbenicillin disodium salt is a semisynthetic compound with antibacterial and β-lactamase-resistant activities and is effective against gram-negative bacteria
• In in vitro studies, carbenicillin disodium salt can totally suppress the proliferation of Agrobacterium

Application

• Due to its antibacterial activity, this compound can be used to control bacterial cell wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. This can lead to incomplete bacterial cell wall synthesis to eventually cause cell lysis
• It has also been used in studies to evaluate the role of penicillin-sensitive transpeptidases in cell wall biosynthesis

Specifications

Chemical Identifiers

• CAS: 4800-94-6
• Molecular Formula: C17H16N2Na2O6S
• Molecular Weight (g/mol): 422.36
• MDL Number: MFCD00077683
• InChI Key: RTYJTGSCYUUYAL-YCAHSCEMSA-L
• PubChem CID: 20933
• ChEBI: CHEBI:34609
• SMILES: [Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)C3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O

• Type: Carbenicillin Disodium Salt
• Physical Form: Powder
• Color: White
• Quantity: 5 g
• Beilstein: 5722128
• Merck Index: 14,1792
• Solubility Information: Soluble in water and alcohol.
• IUPAC Name: disodium;(2S,5R,6R)-6-[(2-carboxylato-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• Formula Weight: 422.36
• Chemical Name or Material: Carbenicillin disodium salt

Safety and Handling

Product Identifier

• Carbenicillin disodium salt

Signal Word

• Danger

Hazard Category

• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : Disodium [2S-(2.alpha.,5.alpha.,6.beta.)]-6-(carboxylatophenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1

RUO – Research Use Only