Invitrogen™ eBioscience™ Brefeldin A Solution (1000X)

Addition of Brefeldin A during the last hours of in vitro activation of cells results in enhanced detection of intracellular cytokines.

Brand:  Invitrogen™ 00-4506-51

Product Code. 15526276

Description

• Brefeldin A is an inhibitor of intracellular protein transport
• Incubation of cells in culture with Brefeldin A leads to blockade of protein transport to the Golgi complex (GC) and accumulation of proteins in the endoplasmic reticulum (ER)
• Brefeldin A is effective for enhanced detection of a majority of mouse and human intracellular cytokines; however, it is advised that the investigators evaluate the use and efficacy of this reagent as well as other protein transport inhibitors such as Monensin in their specific assay system

Specifications

• Quantity: 1 mL
• Product Line: eBioscience™
• Physical Form: Liquid
• Product Type: Inhibitor

Safety and Handling

Product Identifier

• eBioscience Brefeldin A Solution (1000X)

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Flammable liquid Category 2
• Specific target organ toxicity after single exposure Category 1

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H301-Toxic if swallowed.
• H311-Toxic in contact with skin.
• H331-Toxic if inhaled.
• H370-Causes damage to organs.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P264-Wash hands thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P370+P378-In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
• P403+P233-Store in a well-ventilated place. Keep container tightly closed.
• P403+P235-Store in a well-ventilated place. Keep cool.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : methanol

For Research Use Only. Not for use in diagnostic procedures.