Thermo Scientific Chemicals Borate, 0.5M buffer soln., pH 8.5

Description

Borate buffered saline has been used to determine whether heat-killed, borate-buffered suspensions of Gordonia bronchialis, Rhodococcus coprophilus or Tsukamurella inchonensis can be used to treat canine flea allergy. Borate buffered saline has also been used to investigate the effects of lentivirus mediated siRNA targeting human metastasis suppressor 1 (MTSS1, MIM-B gene) gene on the invasive and metastatic potentials of hepatocellular carcinoma (HCC) MHCC97H cells. Borate buffered saline has been used to determine the effects of packaging solution osmolality and buffering agent on soft contact lens parameters. BBS has many uses because it is isotonic and has a strong bactericidal effect. It can be used to dilute substances and in coating procedures. Additives such as Tween 20 and milk powder can be used to add function as washing buffer or blocking buffer. Finfs uses in Protein-coating on microtiter plates, Blocking solution in blots together with Casein or BSA.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Borate buffered saline has been used to determine whether heat-killed, borate-buffered suspensions of Gordonia bronchialis, Rhodococcus coprophilus or Tsukamurella inchonensis can be used to treat canine flea allergy. Borate buffered saline has also been used to investigate the effects of lentivirus mediated siRNA targeting human metastasis suppressor 1 (MTSS1, MIM-B gene) gene on the invasive and metastatic potentials of hepatocellular carcinoma (HCC) MHCC97H cells. Borate buffered saline has been used to determine the effects of packaging solution osmolality and buffering agent on soft contact lens parameters. BBS has many uses because it is isotonic and has a strong bactericidal effect. It can be used to dilute substances and in coating procedures. Additives such as Tween 20 and milk powder can be used to add function as washing buffer or blocking buffer. Finfs uses in Protein-coating on microtiter plates, Blocking solution in blots together with Casein or BSA.

Solubility
Soluble in water 26 g/L (20°C).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specifications

Chemical Identifiers

• CAS: 1330-43-4
• Molecular Formula: B4Na2O7
• Molecular Weight (g/mol): 201.21
• MDL Number: MFCD00081185
• InChI Key: NXSVMNYRVBQCMO-UHFFFAOYSA-N
• IUPAC Name: disodium bicyclo[3.3.1]tetraboroxane-3,7-bis(ylium)-1,5-diuide-1,5-bis(olate)
• SMILES: [Na+].[Na+].[O-][B-]12O[B+]O[B-]([O-])(O[B+]O1)O2

• Concentration: 0.5 M
• pH: 8.5
• Physical Form: Liquid
• Quantity: 250 mL
• Solubility Information: Soluble in water 26g/L (20°C).
• Chemical Name or Material: Borate buffer soln.

Safety and Handling

Product Identifier

• Borate, 0.5M buffer solution, pH 8.5

Signal Word

• Danger

Hazard Category

• Reproductive toxicity Category 1B

Hazard Statement

• H360FD-May damage fertility. May damage the unborn child.

Precautionary Statement

• P201-Obtain special instructions before use.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Boric acid

RUO – Research Use Only