Thermo Scientific Chemicals BICINE, 0.5M buffer soln., pH 8.5

Product Code	Brand	Quantity
15424199	Thermo Scientific Chemicals J61632.AE	100 mL
15434199	Thermo Scientific Chemicals J61632.AK	250 mL

Description

A zwitterionic amino acid buffer agent used for low temperature work. The use of bicine in a thin layer ion exchange chromatography method for protein resolution has been published. Bicine has been utilized in peptide and protein crystallization. A kinetic study of a quaternary transition-state analogue complex of creatine kinase used bicine in the reaction buffer. A multiphasic buffer system for SDS-PAGE of proteins and peptides that incorporates bicine has been described.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
A zwitterionic amino acid buffer agent used for low temperature work. The use of bicine in a thin layer ion exchange chromatography method for protein resolution has been published. Bicine has been utilized in peptide and protein crystallization. A kinetic study of a quaternary transition-state analogue complex of creatine kinase used bicine in the reaction buffer. A multiphasic buffer system for SDS-PAGE of proteins and peptides that incorporates bicine has been described.

Solubility
Soluble in water (1M) at 20°C, ethanol (slightly), ether (slightly), and chloroform (slightly).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Chemical Identifiers

• CAS: 150-25-4
• Molecular Weight (g/mol): 185.16
• InChI Key: MFBDBXAVPLFMNJ-UHFFFAOYSA-M
• ChEBI: CHEBI:40957
• SMILES: [Na+].OCCN(CCO)CC([O-])=O

• Molecular Formula: C6H12NNaO4
• MDL Number: MFCD00004295
• PubChem CID: 8761
• IUPAC Name: 2-[bis(2-hydroxyethyl)amino]acetic acid

Specifications

• CAS: 150-25-4
• pH: 8.5
• Molecular Formula: C6H12NNaO4
• Solubility Information: Soluble in water (1M) at 20°C,ethanol (slightly),ether (slightly),and chloroform (slightly).
• SMILES: [Na+].OCCN(CCO)CC([O-])=O
• Molecular Weight (g/mol): 185.16
• ChEBI: CHEBI:40957

• Concentration: 0.5 M
• Physical Form: Liquid
• MDL Number: MFCD00004295
• InChI Key: MFBDBXAVPLFMNJ-UHFFFAOYSA-M
• IUPAC Name: 2-[bis(2-hydroxyethyl)amino]acetic acid
• PubChem CID: 8761
• Chemical Name or Material: BICINE buffer soln.

Safety and Handling

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only