PKD2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen OSP00018W

Product Code. 11584883

Description

This antibody is directed against the unphosphorylated form of PKD2, and the cross-reactivity with phosphorylated forms has not yet been determined.

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal domit polycystic kidney disease.

Specifications

• Antigen: PKD2
• Classification: Polyclonal
• Gene: PKD2
• Gene Alias: PKD2, Polycystin-2, Autosomal domit polycystic kidney disease type II protein, Polycystwin, R48321
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q13563
• Gene Symbols: PKD2
• Immunogen: A synthetic peptide from the 4th cytoplasmic loop of human Polycystic kidney disease 2 protein
• Regulatory Status: RUO
• Gene ID (Entrez): 5311
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized