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Phospho-p38 MAPK (Thr180, Tyr182) Rabbit anti-Human, Rat, Polyclonal, Invitrogen

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA184807

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 11559220

  • £451.00 / 100µL

Estimated Shipment: 06-07-2021

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Description

Description

Predicted to react with bovine, chicken, dog, monkey, mouse and zebrafish based on sequence homology. For the detection of phosphoproteins, serine phosphatase inhibitors such as 10mM NaF should be added to the sample buffer. Milk or other casein-based blocking solutions are not recommended as casein is a phosphoprotein and its use can result in high background. In Western blot, this antibody detects a band at ∽39kDa in Western blots of anisomycin C-6 glioma cell lysates. Rabbit anti Rat p38 MAPK (pThr180/pTyr182) antibody recognizes mitogen-activated protein kinase p38 (p38 MAPK), also known as mitogen-activated protein kinase 14 (MAPK 14), when phosphorylated at threonine 180 and tyrosine 182.

p38 MAPK is a serine/threonin kinase which plays an important role in signal transduction, contributing to the regulation of many cellular processes including cell differentiation and inflammation. The protein is activated by phosphorylation of threonine 180 and tyrosine 182, by serveral upstream kinases, in response to a wide range of extracellular stimuli such as UV B irradiation and endotoxin exposure.
Specifications

Specifications

Phospho-p38 MAPK (Thr180, Tyr182)
Polyclonal
0.01M HEPES with 0.01% BSA, 50% glycerol and 0.09% sodium azide; pH 7.5
Q15759, Q16539, P70618
RP1-179N16.5, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Rabbit
IgG
100 μL
4°C or -20°C if preferred
Primary
81649, 689314, 1432, 5600
Western Blot
Unconjugated
MAPK14
Liquid
MAPK11, Mapk14
Synthetic phosphopeptide corresponding to an amino acid sequence within p38 MAPK which includes phosphorylated Thr180 and Tyr182.
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
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