Phospho-HDAC4/HDAC5/HDAC7 (Ser246, Ser259, Ser155) Monoclonal Antibody (B.544.8), Invitrogen™

Rabbit Monoclonal Antibody

Brand:  Invitrogen MA514776

Product Code. 11302002

Beschreibung

It is not recommended to aliquot this antibody.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Spezifikation

• Antigen: Phospho-HDAC4/HDAC5/HDAC7 (Ser246, Ser259, Ser155)
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: HDAC4
• Gene Alias: 4932408F19Rik; 5830434K02Rik; AHO3; AI047285; AI426555; Antigen NY-CO-9; BDMR; HA6116; HD4; HD5; HD7; HD7a; Hdac4; HDAC-4; HDAC5; Hdac7; hdac-7; HDAC7A; HDACA; HDAC-A; Histone deacetylase 4; histone deacetylase 5; Histone deacetylase 7; histone deacetylase 7A; histone deacetylase A; histone deacetylase mHDA1; KIAA0288; KIAA0600; mFLJ00062; mHDA1; mKIAA0600; NY-CO-9
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10014, 15184, 208727, 51564, 56233, 9759
• Content And Storage: -20°C
• Form: Liquid

• Applications: ChIP Assay, Western Blot
• Clone: B.544.8
• Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
• Gene Accession No.: P56524, Q6NZM9, Q8C2B3, Q8WUI4, Q9UQL6, Q9Z2V6
• Gene Symbols: HDAC4, HDAC5, HDAC7
• Immunogen: Synthetic phosphopeptide corresponding to pSer155 of human HDAC7 protein
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG