ME1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA521550

Product Code. 13299068

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, NIH-3T3, JC, BCL-1, PC-12. Predicted reactivity: Mouse (91%), Rat (91%), Chicken (80%), Sheep (92%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ME1 encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Specifications

• Antigen: ME1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Me1
• Gene Alias: cytosolic malic enzyme 1; D9Ertd267e; HUMNDME; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+); malate dehydrogenase decarboxylase (NADP+); malic enzyme; malic enzyme 1; malic enzyme 1, NADP(+)-dependent, cytoplasmic (cytosolic, soluble); malic enzyme 1, NADP(+)-dependent, cytosolic; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; malic enzyme, supernatant; Mdh-1; ME1; MES; Mod1; Mod-1; NADP-dependent malic enzyme; NADP-dependent malic enzyme-like protein; NADP-ME; pyruvic-malic carboxylase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17436, 24552, 4199
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.94 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P06801, P13697, P48163
• Gene Symbols: Me1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 161 and 519 of (Uniprot ID#P48163)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG