HSPBAP1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA530817

Product Code. 13425327

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (95%), Rat (96%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488 amino acid cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1. Widely expressed with highest expression in ovary, thymus and pancreas, HSPBAP1 is thought to play a role in mediating cellular stress responses within the cell. Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events. Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis. Three isoforms of HSPBAP1 exist due to alternative splicing events.

Specifications

• Antigen: HSPBAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPBAP1
• Gene Alias: 27 kDa heat shock protein-associated protein 1; 3830421G21Rik; FLJ22623; FLJ39386; Heat shock protein; HSP; HSP27; HSP28; HSPB (heat shock 27kDa) associated protein 1; Hspb associated protein 1; HSPB1 associated protein 1; HSPB1-associated protein 1; HSPBAP1; PASS1; protein associated with small stress protein 1; protein associating with small stress protein PASS1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79663
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96EW2
• Gene Symbols: HSPBAP1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 103 and 319 of Human HSPBAP1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG