FASTK Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA528671

Product Code. 13462787

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4. Predicted reactivity: Mouse (91%), Dog (96%), Pig (92%), Chimpanzee (99%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

Specifications

• Antigen: FASTK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FASTK
• Gene Alias: 0610011K02Rik; 610011K02Rik; Fas activated serine/threonine kinase; Fas-activated serine/threonine kinase; FAST; FAST kinase; Fastk
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10922
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.88 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14296
• Gene Symbols: FASTK
• Immunogen: Recombinant fragment corresponding to a region within amino acids 306 and 549 of Human FAST
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG