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ESRRB Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA526070
Code : LD
Additional Details : Weight : 0.01000kg
Description
ESRRB (steroid hormone receptor ERR2) plays a role in maintenance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation ESRRB interacts with KDM1A by directly binding to enhancer sites of ELF5 and EOMES and activates their transcription leading to self-renewal of trophoblast stem cells. ESSRB also regulates expression of multiple rod-specific genes and is required for survival of this cell type. Defects in the gene can cause deafness, autosomal recessive, 35 (DFNB35).Specifications
ESRRB | |
Polyclonal | |
Unconjugated | |
ESRRB | |
DFNB35; ERR beta-2; ERR2; Err-2; ERRb; ERRB2; ERRbeta; ERR-beta; ERRbeta-2; ESRL2; ESRRB; estrogen receptor related 2; estrogen receptor-like 2; estrogen related receptor beta; estrogen related receptor, beta; estrogen-related nuclear receptor beta; estrogen-related receptor beta; estrogen-related receptor, beta; Estrrb; NR3B2; nuclear receptor ERRB2; nuclear receptor subfamily 3 group B member 2; orphan nuclear receptor; steroid hormone receptor ERR2 | |
Rabbit | |
Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
RUO | |
2103 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
2 mg/mL | |
PBS with 0.09% sodium azide | |
O95718 | |
ESRRB | |
KLH conjugated synthetic peptide between 275-305 amino acids from the central region of human ESRRB | |
400 μL | |
Primary | |
Human | |
Antibody | |
IgG |